Abstract Protein phosphatase 2A (PP2A) plays a critical multi-faceted role in the regulation
of the cell cycle. It is known to dephosphorylate over 300 substrates involved in the cell …

Protein phosphatase 2A (PP 2A) is a serine/threonine phosphatase involved in the
regulation of many cellular processes. A confirmed tumor suppressor protein, PP 2A is …

Protein phosphatase 2A (PP2A) comprises a family of serine/threonine phosphatases,
minimally containing a well conserved catalytic subunit, the activity of which is highly …

Human T cell leukemias can arise from oncogenes activated by specific chromosomal
translocations involving the T cell receptor genes. Here we show that five different T cell …

Human Cdc25C is a dual-specificity protein phosphatase that controls entry into mitosis by
dephosphorylating the protein kinase Cdc2. Throughout interphase, but not in mitosis …

Protein phosphatase 1 (PP1) is a major eukaryotic protein serine/threonine phosphatase
that regulates an enormous variety of cellular functions through the interaction of its catalytic …

Chromosomal translocations in the human acute leukemias rearrange the regulatory and
coding regions of a variety of transcription factor genes. The resultant protein products can …

Ceulemans, Hugo, and Mathieu Bollen. Functional Diversity of Protein Phosphatase-1, a
Cellular Economizer and Reset Button. Physiol Rev 84: 1–39, 2004; 10.1152/physrev …

Homeobox genes comprise a large and essential family of developmental regulators that
are vital for all aspects of growth and differentiation. Although many studies have reported …

The serine/threonine protein phosphatase (PP2A) is a trimeric holoenzyme that plays an
integral role in the regulation of a number of major signaling pathways whose deregulation …