Herpes simplex virus-1 in the brain: the dark side of a sneaky infection

ME Marcocci, G Napoletani, V Protto, O Kolesova… - Trends in …, 2020 - cell.com
Herpes simplex virus-1 (HSV-1) establishes latency preferentially in sensory neurons of
peripheral ganglia. A variety of stresses can induce recurrent reactivations of the virus …

A hitchhiker's guide through the cell: the world according to the capsids of alphaherpesviruses

K Döhner, MC Serrero, A Viejo-Borbolla… - Annual Review of …, 2024 - annualreviews.org
The nucleoplasm, the cytosol, the inside of virions, and again the cytosol comprise the world
in which the capsids of alphaherpesviruses encounter viral and host proteins that support or …

Cytoskeleton—a crucial key in host cell for coronavirus infection

Z Wen, Y Zhang, Z Lin, K Shi… - Journal of molecular cell …, 2020 - academic.oup.com
The emerging coronavirus (CoV) pandemic is threatening the public health all over the
world. Cytoskeleton is an intricate network involved in controlling cell shape, cargo transport …

HSV-1 cytoplasmic envelopment and egress

I Ahmad, DW Wilson - International journal of molecular sciences, 2020 - mdpi.com
Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that
has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA …

Homologous organization of cerebellar pathways to sensory, motor, and associative forebrain

TJ Pisano, ZM Dhanerawala, M Kislin, D Bakshinskaya… - Cell reports, 2021 - cell.com
Cerebellar outputs take polysynaptic routes to reach the rest of the brain, impeding
conventional tracing. Here, we quantify pathways between the cerebellum and forebrain by …

Herpes simplex virus type 1 interactions with the interferon system

K Danastas, M Miranda-Saksena… - International journal of …, 2020 - mdpi.com
The interferon (IFN) system is one of the first lines of defense activated against invading viral
pathogens. Upon secretion, IFNs activate a signaling cascade resulting in the production of …

Mechanisms of pathogen invasion into the central nervous system

MD Cain, H Salimi, MS Diamond, RS Klein - Neuron, 2019 - cell.com
CNS infections continue to rise in incidence in conjunction with increases in
immunocompromised populations or conditions that contribute to the emergence of …

Exploring the Protective Effect of Food Drugs against Viral Diseases: Interaction of Functional Food Ingredients and SARS-CoV-2, Influenza Virus, and HSV

A Ricci, GN Roviello - Life, 2023 - mdpi.com
A complex network of processes inside the human immune system provides resistance
against a wide range of pathologies. These defenses form an innate and adaptive immunity …

Herpes simplex virus: the hostile guest that takes over your home

A Banerjee, S Kulkarni, A Mukherjee - Frontiers in microbiology, 2020 - frontiersin.org
Alpha (α)-herpesviruses (HSV-1 and HSV-2), like other viruses, are obligate intracellular
parasites. They hijack the cellular machinery to survive and replicate through evading the …

Global prevalence and pathogenesis of headache in COVID-19: A systematic review and meta-analysis

E Mutiawati, S Syahrul, M Fahriani, JK Fajar… - …, 2021 - pmc.ncbi.nlm.nih.gov
Background: This study was conducted to determine the prevalence of headache in
coronavirus disease 2019 (COVID-19) and to assess its association as a predictor for …