Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant CNS tumor of
children below 6 months of age. The majority of AT/RTs demonstrate genomic alterations in …

Atypical teratoid rhabdoid tumors (ATRTs) are rare central nervous system tumors that
comprise approximately 1–2% of all pediatric brain tumors; however, in patients less than 3 …

Purpose: Report relevance of molecular groups to clinicopathologic features, germline
SMARCB1/SMARCA4 alterations (GLA), and survival of children with atypical teratoid …

Background Radiation therapy is the most commonly used postsurgical treatment for primary
malignant brain tumors. Consequently, investigating the efficacy of chemotherapeutics …

Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant embryonal central nervous
system tumor commonly affecting children< 3 years of age. It roughly constitutes 1%–2% of …

Atypical teratoid rhabdoid tumors (AT/RT) are characterized by mutations and subsequent
inactivation of SMARCB 1 (INI 1, hSNF 5), a predilection for very young children and an …

Atypical teratoid rhabdoid tumors (ATRT s) are recently defined highly aggressive
embryonal central nervous system tumors with a poor prognosis and no definitive guidelines …

Abstract Introduction. Overexpression of the Polycomb repressive complex 2 (PRC2) subunit
Enhancer of Zeste 2 (EZH2) occurs in several malignancies, including prostate cancer …

Introduction Atypical teratoid rhabdoid tumor (ATRT) is a rare, often lethal brain tumor of
childhood characterized by a complex epigenetic landscape amongst a simple genetic …

Chimeric Antigen Receptor (CAR) T cell therapy has recently begun to be used for solid
tumors such as glioblastoma multiforme. Many children with pediatric malignant brain …