Diarrhea is common in infants (children less than 2 years of age), usually acute, and, if
chronic, commonly caused by allergies and occasionally by infectious agents. Congenital …

Monogenic intestinal epithelial disorders, also known as congenital diarrheas and
enteropathies (CoDEs), are a group of rare diseases that result from mutations in genes that …

Congenital sodium diarrhea (CSD) refers to an intractable diarrhea of intrauterine onset with
high fecal sodium loss. CSD is clinically and genetically heterogeneous. Syndromic CSD is …

BACKGROUND & AIMS: Trichohepatoenteric syndrome (THES) is an autosomal-recessive
disorder characterized by life-threatening diarrhea in infancy, immunodeficiency, liver …

Objective: To assess the effectiveness of the combined use of fecal calprotectin (FC), anti-
Saccharomyces cerevisiae antibody (ASCA), perinuclear staining antineutrophil antibody …

Analysis of vertebrate genome sequences at the turn of the millennium revealed that a vastly
larger repertoire of enzymes execute proteolytic cleavage reactions within the pericellular …

Hypomorphic mutations in the human SPINT2 gene cause a broad spectrum of
abnormalities in organogenesis, including organ and digit duplications, atresia, fistulas …

VACTERL association (sometimes termed “VATER association” depending on which
component features are included) is typically defined by the presence of at least three of the …

Objective Congenital sodium diarrhoea (CSD) refers to a form of secretory diarrhoea with
intrauterine onset and high faecal losses of sodium without congenital malformations. The …

Genome-wide studies of African populations have the potential to reveal powerful insights
into the evolution of our species, as these diverse populations have been exposed to …