Clefts of the lip and/or palate (CLP) are common birth defects of complex aetiology. CLP can
occur in isolation or as part of a broad range of chromosomal, Mendelian or teratogenic …

Vitamins are the organic compounds required by the human body and are considered as
vital nutrients needed in specific amounts. They cannot be synthesized in a sufficient amount …

The fusion of two distinct prominences into one continuous structure is common during
development and typically requires integration of two epithelia and subsequent removal of …

Tissue fusion frequently requires the removal of an epithelium that intervenes distinct
primordia to form one continuous structure. In the mammalian secondary palate, a midline …

Oral Diseases (2011) 17, 584–589 Objective: To explore the risk factors of non‐syndromic
orofacial clefts. Subjects and Methods: A case–control study was conducted in China, 537 …

Cleft palate (CP) is a congenital condition characterized by a complex etiology and limited
diagnostic and therapeutic options. In this study, we delved into the molecular mechanisms …

Nonsyndromic cleft palate (CP) is one of the most common human birth defects and both
genetic and environmental risk factors contribute to its etiology. We conducted a genome …

Genetic studies in humans have demonstrated that Cleft lip with or without cleft palate (CL/P)
have a diverse genetic background and probably environmental factors influencing these …

Orofacial clefts (OFCs) are the second most common birth defect worldwide. The etiology of
OFCs involves complex interactions between genetics and environment. Advances in …

Background The association between active maternal smoking and congenital
malformations is well established, but little is known about the association between …