[HTML][HTML] Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges
Clustered regulatory interspaced short palindromic repeats (CRISPR) has changed
biomedical research and provided entirely new models to analyze every aspect of …
biomedical research and provided entirely new models to analyze every aspect of …
CRISPR/Cas9 genome editing for tissue‐specific in vivo targeting: nanomaterials and translational perspective
Clustered randomly interspaced short palindromic repeats (CRISPRs) and its associated
endonuclease protein, ie, Cas9, have been discovered as an immune system in bacteria …
endonuclease protein, ie, Cas9, have been discovered as an immune system in bacteria …
[HTML][HTML] Retinitis pigmentosa: current clinical management and emerging therapies
XTA Nguyen, L Moekotte, AS Plomp… - International journal of …, 2023 - mdpi.com
Retinitis pigmentosa (RP) comprises a group of inherited retinal dystrophies characterized
by the degeneration of rod photoreceptors, followed by the degeneration of cone …
by the degeneration of rod photoreceptors, followed by the degeneration of cone …
Advancement in precision diagnosis and therapeutic for triple-negative breast cancer: Harnessing diagnostic potential of CRISPR-cas & engineered CAR T-cells …
Cancer is characterized by uncontrolled cell growth, disrupted regulatory pathways, and the
accumulation of genetic mutations. These mutations across different types of cancer lead to …
accumulation of genetic mutations. These mutations across different types of cancer lead to …
[HTML][HTML] Exosomal circular RNA: a signature for lung cancer progression
Membrane vesicles having a diameter of 30–150 nm are known as exosomes. Several
cancer types secrete exosomes, which may contain proteins, circular RNAs (circRNAs) …
cancer types secrete exosomes, which may contain proteins, circular RNAs (circRNAs) …
[HTML][HTML] Evolution of CRISPR/cas systems for precise genome editing
M Hryhorowicz, D Lipiński, J Zeyland - International Journal of Molecular …, 2023 - mdpi.com
The bacteria-derived CRISPR/Cas (an acronym for regularly interspaced short palindromic
repeats/CRISPR-associated protein) system is currently the most widely used, versatile, and …
repeats/CRISPR-associated protein) system is currently the most widely used, versatile, and …
[HTML][HTML] CRISPR/Cas9: A powerful strategy to improve CAR-T cell persistence
W Wei, ZN Chen, K Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
As an emerging treatment strategy for malignant tumors, chimeric antigen receptor T (CAR-
T) cell therapy has been widely used in clinical practice, and its efficacy has been markedly …
T) cell therapy has been widely used in clinical practice, and its efficacy has been markedly …
[HTML][HTML] Recent advances in genome-editing technology with CRISPR/Cas9 variants and stimuli-responsive targeting approaches within tumor cells: a future …
The innovative advances in transforming clustered regularly interspaced short palindromic
repeats-associated protein 9 (CRISPR/Cas9) into different variants have taken the art of …
repeats-associated protein 9 (CRISPR/Cas9) into different variants have taken the art of …
[HTML][HTML] Biomaterials-mediated CRISPR/Cas9 delivery: recent challenges and opportunities in gene therapy
AK Dubey, E Mostafavi - Frontiers in Chemistry, 2023 - frontiersin.org
The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …
holds tremendous potential. This innovative approach combines the advantages of …
[HTML][HTML] CRISPR/Cas9 system: recent applications in immuno-oncology and cancer immunotherapy
C Chen, Z Wang, Y Qin - Experimental Hematology & Oncology, 2023 - Springer
Clustered regulatory interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) is essentially an adaptive immunity weapon in prokaryotes against foreign …
protein 9 (Cas9) is essentially an adaptive immunity weapon in prokaryotes against foreign …