Heme is an essential molecule expressed ubiquitously all through our tissues. Heme plays
major functions in cellular physiology and metabolism as the prosthetic group of diverse …

The heme biosynthetic and catabolic pathways generate pro-and antioxidant compounds,
and consequently, influence cellular sensitivity to oxidants. Heme precursors (δ …

The appearance of heme, an organic ring surrounding an iron atom, in evolution forever
changed the efficiency with which organisms were able to generate energy, utilize gasses …

A blood-sucking habit appeared independently several times in the course of arthropod
evolution. However, from more than a million species of insects and arachnids presently …

The presence of bacteria in the midgut of mosquitoes antagonizes infectious agents, such as
Dengue and Plasmodium, acting as a negative factor in the vectorial competence of the …

There is now abundant evidence that vaccination with defined protein antigens is able to
induce significant immunity to tick infestation. In a limited number of cases, this immunity has …

The bloodsucking hemipteran Rhodnius prolixus is a vector of Chagas' disease, which
affects 7–8 million people today in Latin America. In contrast to other hematophagous …

Formation of malaria pigment or haemozoin is the major route of haem detoxification in the
malaria parasite Plasmodium falciparum as well as several other species of …

Wolbachia are intracellular bacteria that infect a vast range of arthropod species, making
them one of the most prevalent endosymbionts in the world. Wolbachia's stunning …

Haeme metabolism remains a vulnerable problem for the intraerythrocytic Plasmodium
which catabolises haemoglobin as a source of amino acids in an acidic, oxygen-rich …