Local heroes or villains: tissue-resident memory T cells in human health and disease
Tissue-resident memory T (TRM) cells are increasingly associated with the outcomes of
health and disease. TRM cells can mediate local immune protection against infections and …
health and disease. TRM cells can mediate local immune protection against infections and …
A systematic review: the role of resident memory T cells in infectious diseases and their relevance for vaccine development
V Muruganandah, HD Sathkumara, S Navarro… - Frontiers in …, 2018 - frontiersin.org
Background Resident memory T cells have emerged as key players in the immune response
generated against a number of pathogens. Their ability to take residence in non-lymphoid …
generated against a number of pathogens. Their ability to take residence in non-lymphoid …
IL-15 complexes induce migration of resting memory CD8 T cells into mucosal tissues
RT Sowell, JW Goldufsky, M Rogozinska… - The Journal of …, 2017 - journals.aai.org
IL-15 is an essential cytokine known to promote T cell survival and activate the effector
function of memory phenotype CD8 T cells. Blocking IL-15 signals also significantly impacts …
function of memory phenotype CD8 T cells. Blocking IL-15 signals also significantly impacts …
Mucosal vaccine approaches for prevention of HIV and SIV transmission
PA Kozlowski, A Aldovini - Current immunology reviews, 2019 - ingentaconnect.com
Optimal protective immunity to HIV will likely require that plasma cells, memory B cells and
memory T cells be stationed in mucosal tissues at portals of viral entry. Mucosal vaccine …
memory T cells be stationed in mucosal tissues at portals of viral entry. Mucosal vaccine …
Differences in serum IgA responses to HIV-1 gp41 in elite controllers compared to viral suppressors on highly active antiretroviral therapy
R Nabi, Z Moldoveanu, Q Wei, ET Golub, HG Durkin… - PLoS …, 2017 - journals.plos.org
Mechanisms responsible for natural control of human immunodeficiency type 1 (HIV)
replication in elite controllers (EC) remain incompletely defined. To determine if EC generate …
replication in elite controllers (EC) remain incompletely defined. To determine if EC generate …
Impact of poxvirus vector priming, protein coadministration, and vaccine intervals on HIV gp120 vaccine-elicited antibody magnitude and function in infant macaques
B Phillips, GG Fouda, J Eudailey, J Pollara… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Despite success in reducing vertical HIV transmission by maternal antiretroviral therapy,
several obstacles limit its efficacy during breastfeeding, and breast-milk transmission is now …
several obstacles limit its efficacy during breastfeeding, and breast-milk transmission is now …
Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus
F Zhao, ZT Berndsen, N Pedreño-Lopez… - Nature …, 2022 - nature.com
SIVmac239 infection of macaques is a favored model of human HIV infection. However, the
SIVmac239 envelope (Env) trimer structure, glycan occupancy, and the targets and ability of …
SIVmac239 envelope (Env) trimer structure, glycan occupancy, and the targets and ability of …
Antiviral therapy for the sexually transmitted viruses: recent updates on vaccine development
Introduction The sexually transmitted infections (STIs) caused by viruses including human T
cell leukemia virus type-1 (HTLV-1), human immunodeficiency virus-1 (HIV-1), human …
cell leukemia virus type-1 (HTLV-1), human immunodeficiency virus-1 (HIV-1), human …
Rectal acquisition of simian immunodeficiency virus (SIV) SIVmac239 infection despite vaccine-induced immune responses against the entire SIV proteome
MA Martins, L Gonzalez-Nieto, MJ Ricciardi… - Journal of …, 2020 - Am Soc Microbiol
Given the complex biology of human immunodeficiency virus (HIV) and its remarkable
capacity to evade host immune responses, HIV vaccine efficacy may benefit from the …
capacity to evade host immune responses, HIV vaccine efficacy may benefit from the …
Coupling of single molecule, long read sequencing with IMGT/HighV-QUEST analysis expedites identification of SIV gp140-specific antibodies from scFv phage …
SY Han, A Antoine, D Howard, B Chang… - Frontiers in …, 2018 - frontiersin.org
The simian immunodeficiency virus (SIV)/macaque model of human immunodeficiency virus
(HIV)/acquired immunodeficiency syndrome pathogenesis is critical for furthering our …
(HIV)/acquired immunodeficiency syndrome pathogenesis is critical for furthering our …