Comprehensive review of mechanisms of pathogenesis involved in Alzheimer's disease and potential therapeutic strategies
AD is a progressive neurodegenerative disorder and a leading cause of dementia in an
aging population worldwide. The enormous challenge which AD possesses to global …
aging population worldwide. The enormous challenge which AD possesses to global …
Shared mechanisms of neurodegeneration in Alzheimer's disease and Parkinson's disease
A Xie, J Gao, L Xu, D Meng - BioMed research international, 2014 - Wiley Online Library
Alzheimer's disease (AD) and Parkinson's disease (PD) have markedly different clinical and
pathological features, but these two diseases are the most common neurodegenerative …
pathological features, but these two diseases are the most common neurodegenerative …
β-Carboline as a privileged scaffold for multitarget strategies in Alzheimer's disease therapy
A Beato, A Gori, B Boucherle… - Journal of Medicinal …, 2021 - ACS Publications
The natural β-carboline alkaloids display similarities with neurotransmitters that can be
favorably exploited to design bioactive and bioavailable drugs for Alzheimer's disease (AD) …
favorably exploited to design bioactive and bioavailable drugs for Alzheimer's disease (AD) …
A Concise Review of Common Plant-derived Compounds as a Potential Therapy for Alzheimer's Disease and Parkinson's Disease: Insight into Structure-Activity …
S Nishal, P Phaugat, J Bazaad, R Dhaka… - CNS & Neurological …, 2023 - ingentaconnect.com
Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common
neurological illnesses that affect people in their later years. Memory loss is the hallmark of …
neurological illnesses that affect people in their later years. Memory loss is the hallmark of …
Garcinol pacifies acrylamide induced cognitive impairments, neuroinflammation and neuronal apoptosis by modulating GSK signaling and activation of pCREB by …
C Sharma, SC Kang - Food and Chemical Toxicology, 2020 - Elsevier
The presence of acrylamide (ACR) in food results in evident cognitive decline, accumulation
of misfolded proteins, neurotoxicity, neuroinflammation, and neuronal apoptosis leading to …
of misfolded proteins, neurotoxicity, neuroinflammation, and neuronal apoptosis leading to …
Changes in arginine metabolism in advanced Alzheimer's patients: Experimental and theoretical analyses
Limited data obtained in studies conducted in recent years suggest that changes in arginine
metabolism may be associated with the pathogenesis of Alzheimer's disease (AD) …
metabolism may be associated with the pathogenesis of Alzheimer's disease (AD) …
[PDF][PDF] 2D/3D-QSAR, Docking and optimization of 5-substituted-1h-indazole as inhibitors of GSK-3β
N Balakrishnan, JS Raj, N Kandakatla - Int J Pharm Sci, 2014 - academia.edu
Objective: Glycogen synthase kinase-3 beta (GSK-3β) plays a crucial role in several human
diseases. GSK-3β is being one of the most attractive therapeutic targets for several decades …
diseases. GSK-3β is being one of the most attractive therapeutic targets for several decades …
Derivati N-(benzil) piperazinici dell'1, 4-naftochinone con potenziale attività inibitrice delle colinesterasi
E Jashkuri - 2021 - unire.unige.it
Il morbo di Alzheimer (AD) è una malattia neurodegenerativa progressiva ed è una delle
principali cause di deficit cognitivo, perdita di memoria ed alterazioni comportamentali …
principali cause di deficit cognitivo, perdita di memoria ed alterazioni comportamentali …
[HTML][HTML] NDUFA12L mitochondrial complex-I assembly factor: Implications for taupathies
M Salama, WMY Mohamed - Applied & Translational Genomics, 2015 - Elsevier
There is a strong correlation between taupathies and the development and progression of
neurodegenerative disorders. Abnormal tau becomes hyperphosphorylated and dissociated …
neurodegenerative disorders. Abnormal tau becomes hyperphosphorylated and dissociated …