Glucagon-like peptide-1, produced predominantly in enteroendocrine cells, controls glucose
metabolism and energy homeostasis through regulation of islet hormone secretion …

The anorexigenic peptide glucagon-like peptide-1 (GLP-1) is secreted from gut
enteroendocrine cells and brain preproglucagon (PPG) neurons, which, respectively, define …

In addition to regulating the ingestion and digestion of food, sensory feedback from gut to
brain modifies emotional state and motivated behavior by subconsciously shaping cognitive …

The body-brain axis is emerging as a principal conductor of organismal physiology. It
senses and controls organ function1, 2, metabolism3 and nutritional state4-6. Here, we …

Centrally administered glucagon-like peptide 1 (GLP-1) supresses food intake. Here we
demonstrate that GLP-1–producing (PPG) neurons in the nucleus tractus solitarii (NTS) are …

Glucagon like-peptide 1 (GLP-1) within the brain is produced by a population of
preproglucagon neurons located in the caudal nucleus of the solitary tract. These neurons …

Neuroendocrine, behavioural and autonomic responses to stressful stimuli are orchestrated
by complex neural circuits. The caudal nucleus of the solitary tract (cNTS) in the dorsomedial …

Traumatic brain injury (TBI) is a common and often devastating illness, with wide-ranging
public health implications. In addition to the primary injury, victims of TBI are at risk for …

Given the high‐energy requirements to sustain immune responses and healing processes, it
is intriguing that lack of appetite (ie, anorexia) is a cardinal feature of sickness behaviour …

Abstract Glucagon-like peptide-1 (GLP-1) within the brain is a potent regulator of food intake
and most studies have investigated the anorexic effects of central GLP-1. A range of brain …