[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach
The sudden emergence of severe respiratory disease, caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …
[HTML][HTML] Impact of virus genetic variability and host immunity for the success of COVID-19 vaccines
WG Dos Santos - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Abstract Coronavirus disease 19 (COVID-19) continues to challenge most scientists in the
search of an effective way to either prevent infection or to avoid spreading of the disease. As …
search of an effective way to either prevent infection or to avoid spreading of the disease. As …
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase
JA Newman, A Douangamath, S Yadzani… - Nature …, 2021 - nature.com
There is currently a lack of effective drugs to treat people infected with SARS-CoV-2, the
cause of the global COVID-19 pandemic. The SARS-CoV-2 Non-structural protein 13 …
cause of the global COVID-19 pandemic. The SARS-CoV-2 Non-structural protein 13 …
Coronavirus helicases: Attractive and unique targets of antiviral drug-development and therapeutic patents
AN Spratt, F Gallazzi, TP Quinn, CL Lorson… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: Coronaviruses encode a helicase that is essential for viral replication and
represents an excellent antiviral target. However, only a few coronavirus helicase inhibitors …
represents an excellent antiviral target. However, only a few coronavirus helicase inhibitors …
Recent updates in COVID-19 with emphasis on inhalation therapeutics: Nanostructured and targeting systems
The current world health threat posed by the novel coronavirus disease of 2019 (COVID-19)
calls for the urgent development of effective therapeutic options. COVID-19 needs daunting …
calls for the urgent development of effective therapeutic options. COVID-19 needs daunting …
Research progress in porcine reproductive and respiratory syndrome virus–host protein interactions
H Zhang, H Sha, L Qin, N Wang, W Kong, L Huang… - Animals, 2022 - mdpi.com
Simple Summary PRRSV–host protein interactions are of great significance in finding new
antiviral targets. We summarize the effects of all the PRRSV structural and nonstructural …
antiviral targets. We summarize the effects of all the PRRSV structural and nonstructural …
Identification of intrinsically disorder regions in non-structural proteins of SARS-CoV-2: New insights into drug and vaccine resistance
The outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged
in December 2019 and caused coronavirus disease 2019 (COVID-19), which causes …
in December 2019 and caused coronavirus disease 2019 (COVID-19), which causes …
Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression
The arterivirus porcine reproductive and respiratory syndrome virus (PRRSV) causes
significant economic losses to the swine industry worldwide. Here we apply ribosome …
significant economic losses to the swine industry worldwide. Here we apply ribosome …
The function of the PRRSV–host interactions and their effects on viral replication and propagation in antiviral strategies
J Ma, L Ma, M Yang, W Wu, W Feng, Z Chen - Vaccines, 2021 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV) affects the global swine
industry and causes disastrous economic losses each year. The genome of PRRSV is an …
industry and causes disastrous economic losses each year. The genome of PRRSV is an …
Various vaccine platforms in the field of COVID-19
Background With the emergence of Corona virus Disease-2019, a novel worldwide health
disaster is threatening the population. The WHO declared COVID-19 as a pandemic in …
disaster is threatening the population. The WHO declared COVID-19 as a pandemic in …