Unnatural helical peptidic foldamers as protein segment mimics
P Sang, J Cai - Chemical Society Reviews, 2023 - pubs.rsc.org
Unnatural helical peptidic foldamers have attracted considerable attention owing to their
unique folding behaviours, diverse artificial protein binding mechanisms, and promising …
unique folding behaviours, diverse artificial protein binding mechanisms, and promising …
Paramyxoviruses: pathogenesis, vaccines, antivirals, and prototypes for pandemic preparedness
WP Duprex, RE Dutch - The Journal of Infectious Diseases, 2023 - academic.oup.com
The Paramyxoviridae family includes established human pathogens such as measles virus,
mumps virus, and the human parainfluenza viruses; highly lethal zoonotic pathogens such …
mumps virus, and the human parainfluenza viruses; highly lethal zoonotic pathogens such …
Murine parainfluenza virus persists in lung innate immune cells sustaining chronic lung pathology
Common respiratory viruses, including the human parainfluenza viruses, threaten human
health seasonally and associate with the development of chronic lung diseases. Evidence …
health seasonally and associate with the development of chronic lung diseases. Evidence …
Subnanometer structure of an enveloped virus fusion complex on viral surface reveals new entry mechanisms
Paramyxoviruses—including important pathogens like parainfluenza, measles, and Nipah
viruses—use a receptor binding protein [hemagglutinin-neuraminidase (HN) for …
viruses—use a receptor binding protein [hemagglutinin-neuraminidase (HN) for …
A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology
Y Lin, M Khan, B Weynand, M Laporte… - Nature …, 2024 - nature.com
Human parainfluenza virus type 3 (HPIV-3) can cause severe respiratory tract infections.
There are no convenient small-animal infection models. Here, we show viral replication in …
There are no convenient small-animal infection models. Here, we show viral replication in …
Comparison of mutations in human parainfluenza viruses during passage in primary human bronchial/tracheal epithelial air-liquid interface cultures and cell lines
S Sugimoto, M Kawase, R Suwa, Y Kume… - Microbiology …, 2024 - journals.asm.org
Human parainfluenza virus (HPIV) causes respiratory infections, which are exacerbated in
children and older people. Correct evaluation of viral characteristics is essential for the study …
children and older people. Correct evaluation of viral characteristics is essential for the study …
Genetic characteristics of human parainfluenza viruses 1–4 associated with acute lower respiratory tract infection in Chinese children, during 2015–2021
Y Zhu, Y Sun, C Li, G Lu, R Jin, B Xu… - Microbiology …, 2024 - journals.asm.org
Human parainfluenza viruses (HPIVs) are a significant cause of acute lower respiratory tract
infections (ALRTIs) among young children and elderly individuals worldwide. The four types …
infections (ALRTIs) among young children and elderly individuals worldwide. The four types …
Functional and structural basis of human parainfluenza virus type 3 neutralization with human monoclonal antibodies
N Suryadevara, AR Otrelo-Cardoso, N Kose… - Nature …, 2024 - nature.com
Human parainfluenza virus type 3 (hPIV3) is a respiratory pathogen that can cause severe
disease in older people and infants. Currently, vaccines against hPIV3 are in clinical trials …
disease in older people and infants. Currently, vaccines against hPIV3 are in clinical trials …
Evidence of recurrent selection of mutations commonly found in SARS-CoV-2 variants of concern in viruses infecting immunocompromised patients
LR Goes, JD Siqueira, MM Garrido, BM Alves… - Frontiers in …, 2022 - frontiersin.org
Chronically immunosuppressed patients infected with SARS-CoV-2 often experience
prolonged virus shedding, and may pave the way to the emergence of mutations that render …
prolonged virus shedding, and may pave the way to the emergence of mutations that render …
How a paramyxovirus fusion/entry complex adapts to escape a neutralizing antibody
TC Marcink, G Zipursky, EB Sobolik, K Golub… - Nature …, 2024 - nature.com
Paramyxoviruses including measles, Nipah, and parainfluenza viruses are public health
threats with pandemic potential. Human parainfluenza virus type 3 (HPIV3) is a leading …
threats with pandemic potential. Human parainfluenza virus type 3 (HPIV3) is a leading …