The tooth provides an excellent system for deciphering the molecular mechanisms of
organogenesis, and has thus been of longstanding interest to developmental and stem cell …

The tooth root is an integral, functionally important part of our dentition. The formation of a
functional root depends on epithelial-mesenchymal interactions and integration of the root …

The continuously growing mouse incisor serves as a valuable model to study stem cell
regulation during organ renewal. Epithelial stem cells are localized in the proximal end of …

Most characteristics of tooth shape and pattern can be altered by modulating the signal
pathways mediating epithelial–mesenchymal interactions in developing teeth. These …

The ablation of Apc function or the constitutive activation ofβ-catenin in embryonic mouse
oral epithelium results in supernumerary tooth formation, but the underlying mechanisms …

During embryogenesis, ectodermal stem cells adopt different fates and form diverse
ectodermal organs, such as teeth, hair follicles, mammary glands, and salivary glands …

The integument forms a number of different types of mineralized element, including dermal
denticles, scutes, ganoid scales, elasmoid scales, fin rays and osteoderms found in certain …

Mammalian teeth develop from oral ectoderm and neural crest derived mesenchyme. The
first morphological sign is the primary dental lamina forming as a thickening of oral …

Teeth are unique to vertebrates and have played a central role in their evolution. The
molecular pathways and morphogenetic processes involved in tooth development have …

The mouse incisor is a remarkable tooth that grows throughout the animal's lifetime. This
continuous renewal is fueled by adult epithelial stem cells that give rise to ameloblasts …