Oral cancer: deregulated molecular events and their use as biomarkers

N Sinevici, J O'sullivan - Oral oncology, 2016 - Elsevier
Oral Cancer (OC) is a subset of head and neck cancer (HNC) with an annual worldwide
incidence of 275,000 cases. OC remains a significant burden worldwide in terms of …

HER2 as a therapeutic target in head and neck squamous cell carcinoma

NI Pollock, JR Grandis - Clinical Cancer Research, 2015 - AACR
The majority of patients with head and neck squamous cell carcinoma (HNSCC) present
with advanced-stage disease. The current standard of care is surgery followed by adjuvant …

Deacetylated sialic acids modulates immune mediated cytotoxicity via the sialic acid-Siglec pathway

S Grabenstein, KN Barnard, M Anim, A Armoo… - …, 2021 - academic.oup.com
Cancers utilize glycans to evade the immune system via the Sialic acid (Sia)-Siglec (Sialic-
acid-binding immunoglobulin-like lectins) pathway. Specifically, atypical structural forms of …

Targeting HER (ERBB) signaling in head and neck cancer: An essential update

J Zhang, NF Saba, GZ Chen, DM Shin - Molecular aspects of medicine, 2015 - Elsevier
HNC (head and neck cancer) remains the 6th most common carcinoma worldwide. The
suboptimal survival and toxicities observed with conventional approaches warrant …

Salivary levels of ErbB2 and CEA in oral squamous cell carcinoma patients

M Honarmand, L Farhad-Mollashahi… - Asian Pacific Journal …, 2016 - koreascience.kr
Oral squamous cell carcinoma (OSCC) is one of the ten most common causes of cancer
death worldwide. Assessment of molecular changes can help detect and control lesions …

Hormone receptors AR, ER, PR and growth factor receptor Her-2 expression in oral squamous cell carcinoma: Correlation with overall survival, disease-free survival …

Y Adnan, SMA Ali, MS Awan, R Idress, MO Awan… - Plos one, 2022 - journals.plos.org
Oral squamous cell carcinoma (OSCC) comprises most of head and neck neoplasms and is
one of the highest-ranking and lethal cancers in Pakistan due to prevailing mouth habits …

Capecitabine and lapatinib for the first‐line treatment of metastatic/recurrent head and neck squamous cell carcinoma

JM Weiss, S Bagley, WT Hwang, J Bauml, JG Olson… - Cancer, 2016 - Wiley Online Library
BACKGROUND The combination of cisplatin, 5‐fluorouracil, and cetuximab is a standard
treatment for patients with recurrent/metastatic head and neck cancer, with a high rate of …

[HTML][HTML] Expression of HER-2/neu in oral squamous cell carcinoma

S Mirza, N Hadi, S Pervaiz, SZ Khan… - Asian Pacific journal …, 2020 - ncbi.nlm.nih.gov
Background: HER-2/neu is a member of the human epidermal growth factor (HER) family of
transmembrane tyrosine kinases, which is significantly associated with the pathogenesis of …

Human epidermal growth factor receptor 2 neu expression in head and neck squamous cell cancers and its clinicopathological correlation: Results from an Indian …

S Vats, MS Ganesh, A Agarwal - Indian Journal of Pathology and …, 2018 - journals.lww.com
Background: Human epidermal growth factor receptor 2 (HER2)/neuprotooncogene (neu) is
a proven molecular prognostic marker in breast, ovarian, gastric, and ovarian cancers. In …

Her2 expression and gene amplification is rarely detectable in patients with oral squamous cell carcinomas

H Hanken, R Gaudin, A Gröbe… - Journal of oral …, 2014 - Wiley Online Library
Purpose Her2 (ErbB2) transforms cells when overexpressed and is an important therapeutic
target in breast cancer. Contrary to breast cancer, studies on Her2 overexpression and gene …