Over the last 4 decades innovations in biomaterials and medical technology have had a
sustainable impact on the development of biopolymers, titanium/stainless steel and …

Tissue defects caused by diseases or trauma present enormous challenges in regenerative
medicine. Recently, a better understanding of the biological processes underlying tissue …

Hydrogels are of growing interest for the delivery of therapeutics to specific sites in the body.
For use as a delivery vehicle, hydrophilic precursors are usually laden with bioactive …

Conventional stem cell delivery typically utilize administration of directly injection of
allogenic cells or domesticated autogenic cells. It may lead to immune clearance of these …

Regenerative therapies in the musculoskeletal system are based on the suitable application
of cells, biomaterials, and/or factors. For an effective approach, numerous aspects have to …

Mesenchymal stem cells (MSCs) were first discovered by Friedenstein and his colleagues in
1976 from bone marrow. The unique property of these cells was their potential to develop …

Developing biomaterials to promote stem cell proliferation and differentiation is a critical
requirement in tissue engineering and regeneration. Extracellular matrix (ECM) derived from …

Introduction Studies with mesenchymal stem cells (MSCs) are increasing due to their
immunomodulatory, anti-inflammatory and tissue regenerative properties. However, there is …

Peptide-based hydrogels are widely studied and applied in bone repair because of their
good biocompatibility, biodegradability and designability. Peptide-based hydrogels can be …

Collagen is the main component of the extracellular matrix and has shown great promise as
a biomaterial for tissue engineering and regenerative medicine applications. This chapter …