The blood-brain barrier and the blood-cerebrospinal fluid barrier are major obstacles in
central nervous system (CNS) drug delivery, since they block most molecules from entering …

Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

Neurological diseases continue to increase in prevalence worldwide. Combined with the
lack of modifiable risk factors or strongly efficacious therapies, these disorders pose a …

It is well known that the central nervous system (CNS) has a limited regenerative capacity
and that many therapeutic molecules cannot cross the blood brain barrier (BBB). The use of …

The treatment of neurodegenerative and psychiatric disorders remains a challenge in
medical research. Several strategies have been developed over the years, either to …

The process of ionic gelation is one of the easiest ways to develop chitosan nanoparticles
reported so far in the literature. Its success is mainly due to its one-shot synthesis, and to the …

Neuropsychiatric diseases are one of the main causes of disability, affecting millions of
people. Various drugs are used for its treatment, although no effective therapy has been …

Agriculture is a backbone of global economy and most of the population relies on this sector
for their livelihood. Chitosan as a biodegradable material thus can be explored for in various …

Neurodegenerative diseases are progressive conditions that affect the neurons of the
central nervous system (CNS) and result in their damage and death. Neurodevelopmental …

The aim of the present study was the development of human serum albumin nanoparticles
(HSA NPs) as nose-to-brain carrier. To strengthen, the efficacy of nanoparticles as drug …