Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria

I Alav, J Kobylka, MS Kuth, KM Pos, M Picard… - Chemical …, 2021 - ACS Publications
Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

The rotary motor of bacterial flagella

HC Berg - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract Flagellated bacteria, such as Escherichia coli, swim by rotating thin helical
filaments, each driven at its base by a reversible rotary motor, powered by an ion flux. A …

Type III protein secretion systems in bacterial pathogens of animals and plants

CJ Hueck - Microbiology and molecular biology reviews, 1998 - Am Soc Microbiol
Various gram-negative animal and plant pathogens use a novel, sec-independent protein
secretion system as a basic virulence mechanism. It is becoming increasingly clear that …

How bacteria assemble flagella

RM Macnab - Annual Reviews in Microbiology, 2003 - annualreviews.org
▪ Abstract The bacterial flagellum is both a motor organelle and a protein export/assembly
apparatus. It extends from the cytoplasm to the cell exterior. All the protein subunits of the …

The Virulence Plasmid of Yersinia, an Antihost Genome

GR Cornelis, A Boland, AP Boyd… - Microbiology and …, 1998 - Am Soc Microbiol
The 70-kb virulence plasmid enables Yersinia spp.(Yersinia pestis, Y. pseudotuberculosis,
and Y. enterocolitica) to survive and multiply in the lymphoid tissues of their host. It encodes …

The non-flagellar type III secretion system evolved from the bacterial flagellum and diversified into host-cell adapted systems

SS Abby, EPC Rocha - 2012 - journals.plos.org
Type 3 secretion systems (T3SSs) are essential components of two complex bacterial
machineries: the flagellum, which drives cell motility, and the non-flagellar T3SS (NF-T3SS) …

Molecular and functional characterization of the Salmonella invasion gene invA: homology of InvA to members of a new protein family

JE Galan, C Ginocchio, P Costeas - Journal of bacteriology, 1992 - Am Soc Microbiol
One of the earliest steps in the pathogenic cycle of the facultative intracellular pathogen
Salmonella spp. is the invasion of the cells of the intestinal epithelium. We have previously …

Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formation.

KG Jarvis, JA Giron, AE Jerse… - Proceedings of the …, 1995 - National Acad Sciences
Enteropathogenic Escherichia coli (EPEC) causes a characteristic histopathology in
intestinal epithelial cells called the attaching and effacing lesion. Although the …

Isolation, characterization and structure of bacterial flagellar motors containing the switch complex

NR Francis, GE Sosinsky, D Thomas… - Journal of molecular …, 1994 - Elsevier
A putative complex of the three switch proteins, FliG, FliM and FliN appears to be directly
involved in torque generation and control of direction of rotation. We have developed a …

Energy source of flagellar type III secretion

K Paul, M Erhardt, T Hirano, DF Blair, KT Hughes - Nature, 2008 - nature.com
Bacterial flagella contain a specialized secretion apparatus that functions to deliver the
protein subunits that form the filament and other structures to outside the membrane. This …