Mechanisms of disease: Helicobacter pylori virulence factors

Y Yamaoka - Nature reviews Gastroenterology & hepatology, 2010 - nature.com
Helicobacter pylori plays an essential role in the development of various gastroduodenal
diseases; however, only a small proportion of people infected with H. pylori develop these …

Clinical relevance of Helicobacter pylori vacA and cagA genotypes in gastric carcinoma

RM Ferreira, JC Machado, C Figueiredo - Best practice & research Clinical …, 2014 - Elsevier
Helicobacter pylori infection is the major etiological factor of gastric carcinoma. This disease
is the result of a long, multistep, and multifactorial process, which occurs only in a small …

Association of CagA EPIYA-D or EPIYA-C phosphorylation sites with peptic ulcer and gastric cancer risks: A meta-analysis

Q Li, J Liu, Y Gong, Y Yuan - Medicine, 2017 - journals.lww.com
Background: Increasingly, studies have focused on the relationship between Helicobacter
pylori (H pylori) cytotoxin associated gene A protein (CagA) Glu-Pro-Ile-Tyr-Ala (EPIYA)-D …

Prevalence of Helicobacter pylori vacA, cagA, cagE, oipA, iceA, babA2 and babB genotypes in Iranian dyspeptic patients

H Dabiri, F Jafari, K Baghaei, L Shokrzadeh, S Abdi… - Microbial …, 2017 - Elsevier
There is diversity in clinical outcome of Helicobacter pylori infection in different regions.
Microbial, host and environmental factors seem to be reason of such variation. Considering …

[HTML][HTML] Helicobacter pylori in Iran: A systematic review on the association of genotypes and gastroduodenal diseases

E Hosseini, F Poursina, T Van de Wiele… - Journal of research in …, 2012 - ncbi.nlm.nih.gov
Background: Helicobacter pylori (H. pylori) infection is known as a major etiologic factor for a
variety of gastroduodenal diseases. In Iran, with a high rate of H. pylori infection close to …

Appropriate First-Line Regimens to Combat Helicobacter pylori Antibiotic Resistance: An Asian Perspective

M Miftahussurur, Y Yamaoka - Molecules, 2015 - mdpi.com
Asia has the largest population of any continent and the highest incidence of gastric cancer
in the world, making it very important in the context of Helicobacter pylori infection …

The number of Helicobacter pylori CagA EPIYA C tyrosine phosphorylation motifs influences the pattern of gastritis and the development of gastric carcinoma

RM Ferreira, JC Machado, M Leite, F Carneiro… - …, 2012 - Wiley Online Library
Ferreira RM, Machado JC, Leite M, Carneiro F & Figueiredo C (2012) Histopathology 60,
992–998 The number of Helicobacter pylori CagA EPIYA C tyrosine phosphorylation motifs …

Helicobacter pylori Genetic Polymorphisms in Gastric Disease Development

JM Whitmire, DS Merrell - … pylori in Human Diseases: Advances in …, 2019 - Springer
Infecting half of the world's population, Helicobacter pylori is a medically important bacterium
that induces a variety of gastric diseases, including gastritis, peptic ulcer disease, and …

Dramatic increase in SHP2 binding activity of Helicobacter pylori Western CagA by EPIYA-C duplication: its implications in gastric carcinogenesis

L Nagase, T Hayashi, T Senda, M Hatakeyama - Scientific Reports, 2015 - nature.com
Infection with cagA-positive Helicobacter pylori is critically associated with the development
of gastric cancer. The cagA-encoded CagA is delivered into gastric epithelial cells via type …

Prevalence of Helicobacter pylori infection in dyspeptic patients in Iran

L Shokrzadeh, K Baghaei, Y Yamaoka, S Shiota… - Gastroenterology …, 2012 - mdpi.com
Although Helicobacter pylori (H. pylori) infection has been known to be associated with
several upper gastrointestinal disorders such as peptic ulcer and gastric cancer, the …