Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a
mosquito-borne disease of major public health concern associated with significant morbidity …

Dengue viruses (DENVs) cause the most common arthropod-borne viral disease in man
with 50–100 million infections per year. Because of the lack of a vaccine and antiviral drugs …

Abstract Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by the
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) that has quickly and …

Dengue virus (DENV) is a member of the Flavivirus genus of the Flaviviridae family of
enveloped, positive-strand RNA viruses. The Flavivirus genus includes viruses transmitted …

The immunopathogenesis of dengue haemorrhagic fever and dengue shock syndrome is
thought to be mediated by a variety of host factors. Enhancing antibodies are one of the key …

Dengue disease is a mosquito-borne viral disease of expanding geographical range and
incidence. Infection by one of the four serotypes of dengue virus induces a spectrum of …

Flaviviruses are 5′ capped positive-stranded RNA viruses that replicate their genomes
within endoplasmic reticulum-derived vesicles. Flaviviruses are well known to induce …

Dengue viruses (DEN), mosquito-borne members of the family Flaviviridae, are human
pathogens of global significance. The effects of mycophenolic acid (MPA) and ribavirin …

Oxygen and nitrogen radicals are frequently produced during viral infections. These radicals
are not only a physiological mechanism for pathogen clearance but also result in many …

Disease caused by flavivirus infections is an increasing world health problem. Flavivirus
nonstructural protein 5 (NS5) possesses enzymatic activities required for capping and …