[HTML][HTML] Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects

A Sultana, M Zare, V Thomas, TSS Kumar… - Medicine in Drug …, 2022 - Elsevier
Drug delivery can be defined as the group of approaches a drug or pharmacologically active
agent can be transported to the target cell to treat disease or health issue. Conventional …

Aptamer-based targeted delivery of functional nucleic acids

S Xie, W Sun, T Fu, X Liu, P Chen, L Qiu… - Journal of the …, 2023 - ACS Publications
Functional nucleic acid (NA)-based drugs have a broad range of applications since they
allow the alteration and control of gene/protein expression patterns in cells. In principle …

Recent reports on polysaccharide-based materials for drug delivery

J Kurczewska - Polymers, 2022 - mdpi.com
Polysaccharides constitute one of the most important families of biopolymers. Natural
polysaccharide-based drug delivery systems are of constant interest to the scientific …

Delivery of natural products via polysaccharide-based nanocarriers for cancer therapy: a review on recent advances and future challenges

Y Jiang, C Yan, M Li, S Chen, Z Chen, L Yang… - International Journal of …, 2024 - Elsevier
Cancer, caused by uncontrolled proliferation of abnormal cells, has long been a global
public health issue. For decades, natural products have been proven to be an essential …

Multifunctional polymeric micelle-based nucleic acid delivery: Current advances and future perspectives

I Jarak, M Pereira-Silva, AC Santos, F Veiga… - Applied Materials …, 2021 - Elsevier
Nucleic acid (NA) therapeutics are a rapidly growing class of biomedicines with the ability to
manipulate gene expression in potent and specific manner, and with the enormous potential …

Traversing the diverse avenues of exopolysaccharides-based nanocarriers in the management of cancer

P Paul, R Nair, S Mahajan, U Gupta, M Aalhate… - Carbohydrate …, 2023 - Elsevier
Exopolysaccharides are unique polymers generated by living organisms such as algae,
fungi and bacteria to protect them from environmental factors. After a fermentative process …

[HTML][HTML] Micelles as potential drug delivery systems for colorectal cancer treatment

Z Fatfat, M Fatfat, H Gali-Muhtasib - World Journal of …, 2022 - ncbi.nlm.nih.gov
Despite the significant progress in cancer therapy, colorectal cancer (CRC) remains one of
the most fatal malignancies worldwide. Chemotherapy is currently the mainstay therapeutic …

The impact of anionic polymers on gene delivery: how composition and assembly help evading the toxicity-efficiency dilemma

F Richter, K Leer, L Martin, P Mapfumo… - Journal of …, 2021 - Springer
Cationic polymers have been widely studied for non-viral gene delivery due to their ability to
bind genetic material and to interact with cellular membranes. However, their charged …

Emerging natural polymer-based architectured nanotherapeutics for the treatment of cancer

K Kuna, SR Baddam, S Kalagara, PC Akkiraju… - International Journal of …, 2024 - Elsevier
The field of cancer therapy is advancing rapidly, placing a crucial emphasis on innovative
drug delivery systems. The increasing global impact of cancer highlights the need for …

DNA-based nanomaterials as drug delivery platforms for increasing the effect of drugs in tumors

AN Shishparenok, VV Furman, DD Zhdanov - Cancers, 2023 - mdpi.com
Simple Summary The use of drugs based on nucleic acids is a promising direction in
antitumor therapy. Some modified oligonucleotide analogs, such as antisense …