The microenvironment encompasses all components of a tumor other than the cancer cells
themselves. It is highly heterogenous, comprising a cellular component that includes …

Metastasis is a distinct stage of cancer progression that requires the development of
angiogenic blood vessels serving as conduits for tumor cell dissemination. An accumulated …

CD4+ T cells optimize the cytotoxic T cell (CTL) response in magnitude and quality, by
unknown molecular mechanisms. We here present the transcriptomic changes in CTLs …

Myeloid‐derived suppressor cells (MDSCs) promote tumor progression. The mechanisms of
MDSC development during tumor growth remain unknown. Tumor exosomes (T‐exosomes) …

Abstract Matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) are
collectively known as gelatinases whereas MMP-2 is gelatinase-A and MMP-9 is termed as …

Targeted therapies by means of compounds that inhibit a specific target molecule represent
a new perspective in the treatment of cancer. In contrast to conventional chemotherapy …

A number of extensive reviews are available discussing the roles of MMPs in various
aspects of cancer progression from benign tumor formation to overt cancer present with …

Matrix metalloproteinases (MMPs) are a family of more than 28 enzymes that were initially
identified on the basis of their ability to cleave most elements of the extracellular matrix …

We hypothesized that a small molecule CXCR4 antagonist, AMD3100 (AMD), could
augment the mobilization of bone marrow (BM)-derived endothelial progenitor cells (EPCs) …

Caffeic acid phenethyl ester (CAPE) derived from honeybee propolis has been used as a
folk medicine and has several proven biological activities. The present study investigated …