Neurodegenerative disorders are currently incurable devastating diseases which are
characterized by the slow and progressive loss of neurons in specific brain regions …

Alzheimer's disease is the main cause of dementia in the elderly and begins with a subtle
decline in episodic memory followed by a more general decline in overall cognitive abilities …

Alzheimer's disease (AD) is a neurodegenerative disorder that is one of the most
devastating and widespread diseases worldwide, mainly affecting the aging population. One …

Alzheimer's disease (AD) is the most common form of dementia in the elderly population,
affecting over 55 million people worldwide. Histopathological hallmarks of this multifactorial …

Aggregation of α-synuclein leads to the formation of oligomeric intermediates that can
interact with membranes to form pores. However, it is unknown how this leads to cell toxicity …

Aggregation of the misfolded proteins β-amyloid, tau, huntingtin, and α-synuclein is one of
the most important steps in the pathology underlying a wide spectrum of neurodegenerative …

Recent breakthroughs in neuroscience have led to the awareness that we should revise our
traditional mode of thinking and studying the CNS, ie by isolating the privileged network of …

The heterogeneity and complex nature of Alzheimer's disease (AD) is attributed to several
genetic risk factors and molecular culprits. The slow pace and increasing failure rate of …

In this review, we elucidate the mechanisms of A β oligomer toxicity which may contribute to
Alzheimer's disease (AD). In particular, we discuss on the interaction of A β oligomers with …

The presence of amyloid plaques in the brain is a typical characteristic of Alzheimer's
disease (AD). Amyloid plaques are formed from the deposits of aggregated amyloid β …