Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …

Proteins can be the root cause of a disease, and they can be used to cure it. The need to
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …

According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

The precise and large-scale identification of intact glycopeptides is a critical step in
glycoproteomics. Owing to the complexity of glycosylation, the current overall throughput …

Protein glycosylation and other post-translational modifications are involved in potentially all
aspects of human growth and development. Defective glycosylation has adverse effects on …

Site-specific structural characterization of glycoproteins is important for understanding the
exact functional relevance of protein glycosylation. Resulting partly from the multiple layers …

Human milk is a rich source of nutrients and energy, shaped by mammalian evolution to
provide all the nutritive requirements of the newborn. In addition, several molecules in breast …

Antibody glycosylation has been shown to change with various processes. This review
presents mass spectrometric approaches for antibody glycosylation analysis at the level of …

Most secreted and cell membrane proteins in mammals are glycosylated. Many of these
glycoproteins are also prevalent in milk and play key roles in the biomodulatory properties of …