Mesenchymal stem cells (MSCs) are one of the few stem cell types used in clinical practice
as therapeutic agents for immunomodulation and ischemic tissue repair, due to their unique …

Mesenchymal stem cell (MSC) culturing for cell therapies needs a step forward to be
routinely used in clinical settings. Main concerns regard the use of animal origin reagents, in …

Fetal bovine serum (FBS) is a natural medium used in cell cultures containing the large
amount of nutrients necessary for cell growth and is often used for in vitro cultures of animal …

Cell culture‐conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs)
for basic scientific, therapeutic and diagnostic applications. Cell culturing parameters affect …

The constant growth of the population has pushed researchers to find novel protein sources.
A possible solution to this problem has been found in cellular agriculture, specifically in the …

The recent interest in advanced biologic therapies in veterinary medicine has opened up
opportunities for new treatment modalities with considerable clinical potential. Studies with …

Background Trauma-associated peripheral nerve injury is a widespread clinical problem
causing sensory and motor disabilities. Schwann cells (SCs) contribute to nerve …

Introduction To study human physiological and pathological bone remodeling while
addressing the principle of replacement, reduction and refinement of animal experiments …

Human mesenchymal stromal cell (hMSC) therapy has been gaining immense interest in
regenerative medicine and quite recently for its immunomodulatory properties in COVID-19 …

The development of next‐generation biomimetic cardiovascular implants using tissue
engineering concepts can address the existing shortcomings of the clinically available …