Cu-related agents for cancer therapies

C Wang, X Yang, C Dong, K Chai, J Ruan… - Coordination Chemistry …, 2023 - Elsevier
As an indispensable micronutrient, copper (Cu) plays an important role in promoting
metabolism and maintaining various basic biological functions. Copper homeostasis in the …

Green synthesis of copper oxide nanoparticles using Abutilon indicum leaves extract and their evaluation of antibacterial, anticancer in human A549 lung and MDA …

S Sathiyavimal, EF Durán-Lara, S Vasantharaj… - Food and Chemical …, 2022 - Elsevier
In currently, biosynthesis of copper oxide nanoparticles (CuO NPs) are most widely used
numerous in biological applications such as biosensor, energy, medicine, agriculture …

Promising biomedical systems based on copper nanoparticles: synthesis, characterization, and applications

A Vodyashkin, A Stoinova, P Kezimana - Colloids and Surfaces B …, 2024 - Elsevier
Copper and copper oxide nanoparticles (CuNPs) have unique physicochemical properties
that make them highly promising for biomedical applications. This review discusses the …

Exploring the potential of Mg-Zn-Mn-Ca/ZnO composites as a biodegradable alternative for fracture fixation: microstructural, mechanical, and in-vitro biocompatibility …

V Verma, S Singh, K Pal - Composite Structures, 2023 - Elsevier
The current research investigates the microstructural, mechanical, in vitro degradation,
biocompatibility, and in silico biomechanical behaviour of highly alloyed Mg-Zn-Mn-Ca …

Toxicological assessment of Phormidium sp. derived copper oxide nanoparticles for its biomedical and environmental applications

N Asif, R Ahmad, S Fatima, S Shehzadi, T Siddiqui… - Scientific reports, 2023 - nature.com
Driven by the need to biosynthesized alternate biomedical agents to prevent and treat
infection, copper oxide nanoparticles (CuONPs) have surfaced as a promising avenue …

Exploration of polydopamine capped bimetallic oxide (CuO-NiO) nanoparticles inspired by mussels for enhanced and targeted paclitaxel delivery for synergistic breast …

S Singh, K Pal - Applied Surface Science, 2023 - Elsevier
Integration of antitumor drug and metallic nanoparticles in a polymeric nanosystem with
effective properties is an emerging and promising tool to improve tumor treatment …

Folic-acid adorned alginate-polydopamine modified paclitaxel/Zn-CuO nanocomplex for pH triggered drug release and synergistic antitumor efficacy

S Singh, K Pal - International Journal of Biological Macromolecules, 2023 - Elsevier
Targeted chemotherapy is a prominent cancer treatment research trend that intends to boost
the efficacy of drug delivery to cancer cells. The present work aimed to design, a folate …

Polyphenol modified CuO nanorods capped by kappa-carrageenan for controlled paclitaxel release in furnishing targeted chemotherapy in breast carcinoma cells

S Singh, K Pal - International Journal of Biological Macromolecules, 2024 - Elsevier
The present work deals with the construction of a nanoscale system that can deliver
chemotherapeutic agents to breast cancer cells in a controlled trend. The framework …

Actively targeted gold-polydopamine (PDA@ Au) nanocomplex for sequential drug release and combined synergistic chemo-photothermal therapeutic effects

S Singh, K Pal - International Journal of Pharmaceutics, 2023 - Elsevier
Multifunctional nanoparticles for treatment in cancer are getting more and more attention
recently. In this study, we employed a novel polydopamine (PDA) framework-based gold …

NIR-responsive 5-Fluorouracil delivery using polydopamine coated polygonal CuS nanoplates for synergistic chemo-photothermal therapy on breast cancer

K Pal, P Mahato, S Singh, P Roy - Journal of Drug Delivery Science and …, 2023 - Elsevier
Herein, copper sulfide covellite nanoplates were developed by precipitating Cu 2+ cations in
an aqueous solution using H 2 S gas. The polygonal CuS nanoplates were further coated …