Cell sources for in vitro human liver cell culture models

K Zeilinger, N Freyer, G Damm… - Experimental …, 2016 - journals.sagepub.com
In vitro liver cell culture models are gaining increasing importance in pharmacological and
toxicological research. The source of cells used is critical for the relevance and the …

A serum-free medium suitable for maintaining cell morphology and liver-specific function in induced human hepatocytes

PP Li, C Gu, BY Liang, L Wang, Y Zhou, WS Tan - Cytotechnology, 2019 - Springer
Abstract hiHep is a new type of hepatocyte-like cell that is predicted to be a potential
unlimited source of hepatocytes for a bioartificial liver. However, hiHep cannot currently be …

Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes

F Alsaeedi, R Wilson, C Candlish, I Ibrahim, AC Leitch… - Plos one, 2019 - journals.plos.org
The rat pancreatic AR42J-B13 (B-13) cell line differentiates into non-replicative hepatocyte-
like (B-13/H) cells in response to glucocorticoid. Since this response is dependent on an …

Potentiating stem cell-derived hepatocyte function

FA Alsaeedi - 2020 - theses.ncl.ac.uk
The rat pancreatic AR42J-B13 (B-13) cell line differentiates into non-replicative hepatocyte-
like (B-13/H) cells in response to glucocorticoid. As this response is dependent on the …

[PDF][PDF] Investigation of experimental cell lines and non-invasive online sensor technologies in a 3D bioreactor system for extracorporeal liver support therapy

M Richter - 2016 - depositonce.tu-berlin.de
Liver transplantation is currently the only successful treatment to cure acute or acute-on-
chronic liver failure. However, the number of patients waiting for a donor organ is constantly …