Systematic reviews of systematic reviews identify good quality reviews of earlier studies of
medical conditions. This article describes a systematic review of systematic reviews …

Background Recently, with improvements in computed tomography angiography and digital
subtraction angiography, the assessment of certain morphologic traits of anterior …

Background The natural history of unruptured cerebral aneurysms has not been clearly
defined. Methods From January 2001 through April 2004, we enrolled patients with newly …

Backgrounds and Purpose—The authors evaluated the incidence of rupture of unruptured
intracranial saccular aneurysm during observation. Methods—Between January 2003 and …

Intracranial aneurysms are acquired lesions (5–10% of the population), a fraction of which
rupture leading to subarachnoid hemorrhage with devastating consequences. Until now, the …

Background: Cerebral aneurysms carry a high risk of rupture and so present a major threat
to the patient's life. Accurate criteria for predicting aneurysm rupture are important for …

Intracranial aneurysms are pathological enlargements of brain arteries that are believed to
arise from progressive wall degeneration and remodeling. Earlier work using classical …

Aneurysmal subarachnoid hemorrhage (aSAH) is the most serious subtype of stroke.
Genetic factors have been known to play an important role in the development of intracranial …

OBJECTIVE: Determining factors predictive of the natural risk of rupture of cerebral
aneurysms is difficult because of the need to control for confounding variables. We studied …

Background and Purpose—Knowledge about risk factors contributes to understanding the
pathophysiological mechanisms that cause intracranial aneurysm rupture and helps to …