Immune response and molecular mechanisms of cardiovascular adverse effects of spike proteins from SARS-CoV-2 and mRNA vaccines
The SARS-CoV-2 (severe acute respiratory syndrome coronavirus responsible for the
COVID-19 disease) uses the Spike proteins of its envelope for infecting target cells …
COVID-19 disease) uses the Spike proteins of its envelope for infecting target cells …
Blood-brain barrier function in response to SARS-CoV-2 and its spike protein
Ł Suprewicz, K Fiedoruk… - Neurologia i …, 2023 - journals.viamedica.pl
The typical manifestation of coronavirus 2 (CoV-2) infection is a severe acute respiratory
syndrome (SARS) accompanied by pneumonia (COVID-19). However, SARS-CoV-2 can …
syndrome (SARS) accompanied by pneumonia (COVID-19). However, SARS-CoV-2 can …
SARS-CoV-2 structural proteins modulated blood-testis barrier-related proteins through autophagy in the primary sertoli cells
K Kang, YD Ma, SQ Liu, RW Huang, JJ Chen, LL An… - Viruses, 2023 - mdpi.com
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disrupts the blood-
testis barrier (BTB), resulting in alterations in spermatogenesis. However, whether BTB …
testis barrier (BTB), resulting in alterations in spermatogenesis. However, whether BTB …
Towards Novel Biomimetic In Vitro Models of the Blood–Brain Barrier for Drug Permeability Evaluation
Current available animal and in vitro cell-based models for studying brain-related
pathologies and drug evaluation face several limitations since they are unable to reproduce …
pathologies and drug evaluation face several limitations since they are unable to reproduce …
Acute severe hypoglycemia alters mouse brain microvascular proteome
Hypoglycemia increases the risk related to stroke and neurodegenerative diseases,
however, the underlying mechanisms are unclear. For the first time, we studied the effect of a …
however, the underlying mechanisms are unclear. For the first time, we studied the effect of a …
[HTML][HTML] An integrated bioinformatics approach reveals the potential role of microRNA-30b-5p and let-7a-5p during SARS CoV-2 spike-1 mediated neuroinflammation
P Pawar, K Akolkar, V Saxena - International Journal of Biological …, 2024 - Elsevier
SARS-CoV-2 induced neuroinflammation contributing to neurological sequelae is one of the
critical outcomes of long-COVID, however underlying regulatory mechanisms involved …
critical outcomes of long-COVID, however underlying regulatory mechanisms involved …
Negative regulation of angiogenesis and the MAPK pathway may be a shared biological pathway between IS and epilepsy
L Fu, B Yu, B Lv, Y Tian, Y Zhang, H Chen, S Yang… - Plos one, 2023 - journals.plos.org
Ischemia stroke and epilepsy are two neurological diseases that have significant patient and
societal burden, with similar symptoms of neurological deficits. However, the underlying …
societal burden, with similar symptoms of neurological deficits. However, the underlying …
Protein profiling and assessment of amyloid beta levels in plasma in canine refractory epilepsy
S Phochantachinda, B Chantong… - Frontiers in Veterinary …, 2023 - frontiersin.org
Introduction The relationship between epilepsy and cognitive dysfunction has been
investigated in canines, and memory impairment was prevalent in dogs with epilepsy …
investigated in canines, and memory impairment was prevalent in dogs with epilepsy …
Gender-specific dysregulations of nondifferentially expressed biomarkers of metastatic colon cancer
M Duan, Y Liu, D Zhao, H Li, G Zhang, H Liu… - … Biology and Chemistry, 2023 - Elsevier
Colon cancer is a common cancer type in both sexes and its mortality rate increases at the
metastatic stage. Most studies exclude nondifferentially expressed genes from biomarker …
metastatic stage. Most studies exclude nondifferentially expressed genes from biomarker …
Decreased plasma gelsolin in the COVID-19-related acute respiratory distress syndrome
Objectives The aim of this study was to evaluate the potential roles of plasma gelsolin
(pGSN), transforming growth factor-beta1 (TGF-β1), and lysophosphatidic acid (LPA) as …
(pGSN), transforming growth factor-beta1 (TGF-β1), and lysophosphatidic acid (LPA) as …