A plethora of biochemical signals provides spatial and temporal cues that carefully
orchestrate the complex process of vertebrate embryonic development. The embryonic …

Gradual collagen recruitment has been hypothesized as the underlying mechanism for the
mechanical stiffening with increasing stress in arteries. In this work, we investigated this …

Intracranial aneurysms are pathological enlargements of brain arteries that are believed to
arise from progressive wall degeneration and remodeling. Earlier work using classical …

Innovative research on the interactions between biomechanical load and cardiovascular
(CV) morphogenesis by multiple investigators over the past 3 decades, including the …

We develop efficient numerical methods for fractional order PDEs, and employ them to
investigate viscoelastic constitutive laws for arterial wall mechanics. Recent simulations …

The proper functioning of the arterial wall is vital to the health of the individual, as evidenced
by the numerous debilitating medical problems which can arise when the wall falls prey to …

We develop a loosely coupled fluid‐structure interaction finite element solver based on the
Lie operator splitting scheme. The scheme is applied to the interaction between an …

A well-timed modification of both the collagen and elastic fiber network in the cervix during
pregnancy accompanies the evolution of tissue mechanical parameters that are key to a …

Although uniaxial tensile testing is commonly used to evaluate failure properties of vascular
tissue, there is no established protocol for specimen shape or gripping method. Large …

Inflammation, airway hyper-responsiveness and airway remodelling are well-established
hallmarks of asthma, but their inter-relationships remain elusive. In order to obtain a better …