miRNAs as potential game-changers in renal cell carcinoma: Future clinical and medicinal uses
Renal cell carcinoma (RCC) has the highest mortality rate of all genitourinary cancers, and
its prevalence has grown over time. While RCC can be surgically treated and recurrence is …
its prevalence has grown over time. While RCC can be surgically treated and recurrence is …
[HTML][HTML] Noncoding RNAs related to the hedgehog pathway in cancer: clinical implications and future perspectives
J Song, Y Ge, X Sun, Q Guan, S Gong, M Wei, J Niu… - Molecular cancer, 2022 - Springer
Cancer is a type of malignant affliction threatening human health worldwide; however, the
molecular mechanism of cancer pathogenesis remains to be elusive. The oncogenic …
molecular mechanism of cancer pathogenesis remains to be elusive. The oncogenic …
[HTML][HTML] Circular RNA circPOLR2A promotes clear cell renal cell carcinoma progression by facilitating the UBE3C-induced ubiquitination of PEBP1 and, thereby …
Z Xu, S Chen, R Liu, H Chen, B Xu, W Xu, M Chen - Molecular Cancer, 2022 - Springer
Background Increasing evidence has demonstrated that circular RNAs (circRNAs) are
implicated in cancer progression. However, the aberrant expression and biological functions …
implicated in cancer progression. However, the aberrant expression and biological functions …
[HTML][HTML] Transfection with Plasmid-Encoding lncRNA-SLERCC nanoparticle-mediated delivery suppressed tumor progression in renal cell carcinoma
Background The accumulating evidence confirms that long non-coding RNAs (lncRNAs)
play a critical regulatory role in the progression of renal cell carcinoma (RCC). But, the …
play a critical regulatory role in the progression of renal cell carcinoma (RCC). But, the …
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer
Y Yang, D Luo, Y Shao, Z Shan, Q Liu… - Cancer …, 2023 - Wiley Online Library
Abstract Background Circular RNAs (circRNAs) generated by back‐splicing of precursor
mRNAs (pre‐mRNAs) are often aberrantly expressed in cancer cells. Accumulating …
mRNAs (pre‐mRNAs) are often aberrantly expressed in cancer cells. Accumulating …
Circular RNA Pvt1 oncogene (CircPVT1) promotes the progression of papillary thyroid carcinoma by activating the Wnt/β-catenin signaling pathway and modulating …
L Zeng, S Yuan, P Zhou, J Gong, X Kong, M Wu - Bioengineered, 2021 - Taylor & Francis
Circular RNAs (circRNAs) have been reported to be involved in the progression of papillary
thyroid carcinoma (PTC). However, the role of circular RNA Pvt1 oncogene (circPVT1) in …
thyroid carcinoma (PTC). However, the role of circular RNA Pvt1 oncogene (circPVT1) in …
Circular RNA KIF4A promotes liver metastasis of breast cancer by reprogramming glucose metabolism
J Huang, X Deng, X Chen, Z Chang, Q Lu… - Journal of …, 2022 - Wiley Online Library
Background. Circular RNAs (circRNAs) regulate complex functional processes and play
crucial roles in cancer development and progression. It was reported that circKIF4 regulates …
crucial roles in cancer development and progression. It was reported that circKIF4 regulates …
The role of circular RNA during the urological cancer metastasis: exploring regulatory mechanisms and potential therapeutic targets
Y Xu, Z Gao, X Sun, J Li, T Ozaki, D Shi, M Yu… - Cancer and Metastasis …, 2024 - Springer
Metastasis is a major contributor to treatment failure and death in urological cancers,
representing an important biomedical challenge at present. Metastases form as a result of …
representing an important biomedical challenge at present. Metastases form as a result of …
[HTML][HTML] CircZBTB44 promotes renal carcinoma progression by stabilizing HK3 mRNA structure
T Li, Y Gu, B Xu, K Kuca, J Zhang, W Wu - Molecular Cancer, 2023 - Springer
Abstract CircZBTB44 (hsa_circ_0002484) has been identified to be upregulated in renal cell
carcinoma (RCC) tissues, while its role and contribution in RCC remain elusive. We …
carcinoma (RCC) tissues, while its role and contribution in RCC remain elusive. We …
[HTML][HTML] CircRNAs in lung cancer-role and clinical application
J Li, Q Zhang, D Jiang, J Shao, W Li, C Wang - Cancer Letters, 2022 - Elsevier
Lung cancer holds the highest mortality rate among malignancies worldwide. Nevertheless,
the potential molecular mechanisms of its tumorigenesis and evolution remain obscure …
the potential molecular mechanisms of its tumorigenesis and evolution remain obscure …