BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction
M Zhao, L Chen, J Yang, D Han, D Fang, X Qiu… - Journal of affective …, 2018 - Elsevier
Background Depression is thought to be multifactorial in etiology, including genetic and
environmental components. While a number of gene-environment interaction studies have …
environmental components. While a number of gene-environment interaction studies have …
Gene-environment interactions between stress and 5-HTTLPR in depression: A meta-analytic update
Background Meta-analyses have yielded contradictory findings concerning the role of 5-
HTTLPR in interaction with stress (GxE) in depression. The current meta-analysis …
HTTLPR in interaction with stress (GxE) in depression. The current meta-analysis …
A unified model of depression: Integrating clinical, cognitive, biological, and evolutionary perspectives
AT Beck, K Bredemeier - Clinical Psychological Science, 2016 - journals.sagepub.com
We propose that depression can be viewed as an adaptation to conserve energy after the
perceived loss of an investment in a vital resource such as a relationship, group identity, or …
perceived loss of an investment in a vital resource such as a relationship, group identity, or …
Childhood adversities and depression in adulthood: Current findings and future directions.
RT Liu - Clinical psychology: science and practice, 2017 - psycnet.apa.org
Considerable support exists establishing a relationship between childhood adversities and
adult depression. Consistent evidence has emerged linking early life adversities with a more …
adult depression. Consistent evidence has emerged linking early life adversities with a more …
Adverse childhood experiences, the serotonergic system, and depressive and anxiety disorders in adulthood: a systematic literature review
RK Lipsky, CC McDonald, MC Souders… - Neuroscience & …, 2022 - Elsevier
Background Recent studies have examined the role that the serotonergic system plays in
moderating the association between adverse childhood experiences (ACEs) and depressive …
moderating the association between adverse childhood experiences (ACEs) and depressive …
[HTML][HTML] The relationship between occupational stress, musculoskeletal disorders and the mental health of coal miners: The interaction between BDNF gene, TPH2 …
X Li, T Jiang, X Sun, X Yong, X Ma, J Liu - Journal of Psychiatric Research, 2021 - Elsevier
Objective Mental disorders are prevalent among the population and seriously endanger
people's working ability as well as their physical and mental health. This study employed …
people's working ability as well as their physical and mental health. This study employed …
Exploration of the moderating effects of physical activity and early life stress on the relation between brain-derived neurotrophic factor (BDNF) rs6265 variants and …
CT Soler, SH Kanders, S Olofsdotter, S Vadlin… - Genes, 2022 - mdpi.com
Depression affects one in five persons at 18 years of age. Allele A of the brain-derived
neurotrophic factor (BDNF) rs6265 is considered to be a risk factor for depression. Previous …
neurotrophic factor (BDNF) rs6265 is considered to be a risk factor for depression. Previous …
Interplay between pro-inflammatory cytokines, childhood trauma, and executive function in depressed adolescents
AT Peters, X Ren, KL Bessette, BI Goldstein… - Journal of psychiatric …, 2019 - Elsevier
Background Pro-inflammatory cytokines have been linked to depression, early childhood
trauma, and impairment in executive function in adults. Whether these links are present …
trauma, and impairment in executive function in adults. Whether these links are present …
The roles of early-life adversity and rumination in neural response to emotional faces amongst anxious and depressed adults
AT Peters, KL Burkhouse, KL Kinney… - Psychological …, 2019 - cambridge.org
BackgroundEarly-life adversity (ELA) is a risk factor for internalizing psychopathology (IP).
ELA is also linked to alterations in neural phenotypes of emotion processing and …
ELA is also linked to alterations in neural phenotypes of emotion processing and …
Time moderates the interplay between 5-HTTLPR and stress on depression risk: gene x environment interaction as a dynamic process
C Delli Colli, M Borgi, S Poggini, F Chiarotti… - Translational …, 2022 - nature.com
The serotonin-transporter-linked promoter region (5-HTTLPR) has been widely investigated
as contributing to depression vulnerability. Nevertheless, empirical research provides wide …
as contributing to depression vulnerability. Nevertheless, empirical research provides wide …