Endothelial dysfunction in heart failure with preserved ejection fraction: what are the experimental proofs?
L Cornuault, P Rouault, C Duplàa, T Couffinhal… - Frontiers in …, 2022 - frontiersin.org
Heart failure with preserved ejection fraction (HFpEF) has been recognized as the greatest
single unmet need in cardiovascular medicine. Indeed, the morbi-mortality of HFpEF is high …
single unmet need in cardiovascular medicine. Indeed, the morbi-mortality of HFpEF is high …
[HTML][HTML] The NO-cGMP-PKG axis in HFpEF: from pathological mechanisms to potential therapies
Z Cai, C Wu, Y Xu, J Cai, M Zhao, L Zu - Aging and disease, 2023 - ncbi.nlm.nih.gov
Heart failure with preserved ejection fraction (HFpEF) accounts for almost half of all heart
failure (HF) cases worldwide. Unfortunately, its incidence is expected to continue to rise, and …
failure (HF) cases worldwide. Unfortunately, its incidence is expected to continue to rise, and …
Combination sodium nitrite and hydralazine therapy attenuates heart failure with preserved ejection fraction severity in a “2‐Hit” Murine Model
Background Recent studies have suggested that cardiac nitrosative stress mediated by
pathological overproduction of nitric oxide (NO) via inducible NO synthase (iNOS) …
pathological overproduction of nitric oxide (NO) via inducible NO synthase (iNOS) …
Current understanding of molecular pathophysiology of heart failure with preserved ejection fraction
H Budde, R Hassoun, A Mügge, Á Kovács… - Frontiers in …, 2022 - frontiersin.org
Heart Failure (HF) is the most common cause of hospitalization in the Western societies. HF
is a heterogeneous and complex syndrome that may result from any dysfunction of systolic …
is a heterogeneous and complex syndrome that may result from any dysfunction of systolic …
Improved vascular function and functional capacity following l-citrulline administration in patients with heart failure with preserved ejection fraction: a single-arm, open …
SM Ratchford, K Bunsawat… - Journal of Applied …, 2023 - journals.physiology.org
There is accumulating evidence for both peripheral vascular dysfunction and impaired
functional capacity in patients with heart failure with a preserved ejection fraction (HFpEF) …
functional capacity in patients with heart failure with a preserved ejection fraction (HFpEF) …
Myocardial metabolic reprogramming in HFpEF
Z Zhang, M Sun, W Jiang, L Yu, C Zhang… - Journal of Cardiovascular …, 2024 - Springer
Heart failure (HF) caused by structural or functional cardiac abnormalities is a significant
cause of morbidity and mortality worldwide. While HF with reduced ejection fraction (HErEF) …
cause of morbidity and mortality worldwide. While HF with reduced ejection fraction (HErEF) …
The efficacy and safety of soluble guanylate cyclase modulation in patients with heart failure: a comprehensive meta-analysis of randomized controlled trials
Soluble guanylate cyclase (sGC) modulation has been scrutinized in several disease states
including heart failure (HF). Recently, it was shown that an sGC modulator improved HF …
including heart failure (HF). Recently, it was shown that an sGC modulator improved HF …
[PDF][PDF] Current Understanding of Molecular Pathophysiology of Heart Failure With Preserved Ejection Fraction. Front. Physiol. 13: 928232. doi: 10.3389/fphys …
H Budde, R Hassoun, A Mügge, Á Kovács… - … in Physiology| www …, 2022 - dea.lib.unideb.hu
Heart Failure (HF) is the most common cause of hospitalization in the Western societies. HF
is a heterogeneous and complex syndrome that may result from any dysfunction of systolic …
is a heterogeneous and complex syndrome that may result from any dysfunction of systolic …