Molecular mechanisms of western diet-induced obesity and obesity-related carcinogenesis—A narrative review

D Lathigara, D Kaushal, RB Wilson - Metabolites, 2023 - mdpi.com
The present study aims to provide a narrative review of the molecular mechanisms of
Western diet-induced obesity and obesity-related carcinogenesis. A literature search of the …

Intratumoural microbiota: a new frontier in cancer development and therapy

Y Cao, H Xia, X Tan, C Shi, Y Ma, D Meng… - … and Targeted Therapy, 2024 - nature.com
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several
physiological and pathological processes. Some studies discovered that tumour tissues …

[HTML][HTML] Functional biotransformation of phytoestrogens by gut microbiota with impact on cancer treatment

EK Farhat, EK Sher, A Džidić-Krivić, I Banjari… - The Journal of Nutritional …, 2023 - Elsevier
The human gut is a host for trillions of microorganisms, divided into more than 3,000
heterogeneous species that is called the gut microbiota. The gut microbiota composition can …

Advancements in 3D cell culture systems for personalizing anti-cancer therapies

AMK Law, L Rodriguez de la Fuente, TJ Grundy… - Frontiers in …, 2021 - frontiersin.org
Over 90% of potential anti-cancer drug candidates results in translational failures in clinical
trials. The main reason for this failure can be attributed to the non-accurate pre-clinical …

[HTML][HTML] Breast cancer: molecular mechanisms of underlying resistance and therapeutic approaches

M Tufail, J Cui, C Wu - American journal of cancer research, 2022 - ncbi.nlm.nih.gov
Breast cancer (BC) affects over 250,000 women in the US each year. Drug-resistant cancer
cells are responsible for most breast cancer fatalities. Scientists are developing novel …

The gut microbiome and female health

R Siddiqui, Z Makhlouf, AM Alharbi, H Alfahemi… - Biology, 2022 - mdpi.com
Simple Summary A plethora of studies have highlighted the profound role of the gut
microbiome in human health. However, there is a lack of studies on female health. Given …

[HTML][HTML] Acupuncture ameliorates breast cancer-related fatigue by regulating the gut microbiota-gut-brain axis

Z Lv, R Liu, K Su, Y Gu, L Fang, Y Fan, J Gao… - Frontiers in …, 2022 - frontiersin.org
Cancer-related fatigue (CRF) is the most common side effect of chemotherapy for breast
cancer (BC). Acupuncture treatment has an anti-fatigue effect and can regulate gut …

Human microbiota and immunotherapy in breast cancer-a review of recent developments

M Vitorino, S Baptista de Almeida… - Frontiers in …, 2022 - frontiersin.org
Breast cancer (BC) is the most common malignancy and the second cause of cancer-
specific death in women from high-income countries. Infectious agents are the third most …

Obesity, dysbiosis and inflammation: Interactions that modulate the efficacy of immunotherapy

AS Yende, D Sharma - Frontiers in Immunology, 2024 - frontiersin.org
Recent years have seen an outstanding growth in the understanding of connections
between diet-induced obesity, dysbiosis and alterations in the tumor microenvironment. Now …

The conundrum of breast cancer and microbiome-a comprehensive review of the current evidence

A Papakonstantinou, P Nuciforo, M Borrell… - Cancer Treatment …, 2022 - Elsevier
Disturbance of the microbial balance of a habitat can have detrimental effects on the health
of the individual and, in addition, polymorphic microbiomes were recently suggested as …