Dendritic computation

M London, M Häusser - Annu. Rev. Neurosci., 2005 - annualreviews.org
One of the central questions in neuroscience is how particular tasks, or computations, are
implemented by neural networks to generate behavior. The prevailing view has been that …

Modeling single-neuron dynamics and computations: a balance of detail and abstraction

AVM Herz, T Gollisch, CK Machens, D Jaeger - science, 2006 - science.org
The fundamental building block of every nervous system is the single neuron.
Understanding how these exquisitely structured elements operate is an integral part of the …

An anatomically constrained model for path integration in the bee brain

T Stone, B Webb, A Adden, NB Weddig, A Honkanen… - Current Biology, 2017 - cell.com
Path integration is a widespread navigational strategy in which directional changes and
distance covered are continuously integrated on an outward journey, enabling a straight-line …

Temporal dendritic heterogeneity incorporated with spiking neural networks for learning multi-timescale dynamics

H Zheng, Z Zheng, R Hu, B Xiao, Y Wu, F Yu… - Nature …, 2024 - nature.com
It is widely believed the brain-inspired spiking neural networks have the capability of
processing temporal information owing to their dynamic attributes. However, how to …

Synaptic theory of working memory

G Mongillo, O Barak, M Tsodyks - Science, 2008 - science.org
It is usually assumed that enhanced spiking activity in the form of persistent reverberation for
several seconds is the neural correlate of working memory. Here, we propose that working …

A flexible model of working memory

F Bouchacourt, TJ Buschman - Neuron, 2019 - cell.com
Working memory is fundamental to cognition, allowing one to hold information" in mind." A
defining characteristic of working memory is its flexibility: we can hold anything in mind …

Flexible control of mutual inhibition: a neural model of two-interval discrimination

CK Machens, R Romo, CD Brody - Science, 2005 - science.org
Networks adapt to environmental demands by switching between distinct dynamical
behaviors. The activity of frontal-lobe neurons during two-interval discrimination tasks is an …

Memory traces in dynamical systems

S Ganguli, D Huh… - Proceedings of the …, 2008 - National Acad Sciences
To perform nontrivial, real-time computations on a sensory input stream, biological systems
must retain a short-term memory trace of their recent inputs. It has been proposed that …

Persistent neural activity: prevalence and mechanisms

G Major, D Tank - Current opinion in neurobiology, 2004 - Elsevier
Persistent neural activity refers to a sustained change in action potential discharge that long
outlasts a stimulus. It is found in a diverse set of brain regions and organisms and several in …

Bistability of cerebellar Purkinje cells modulated by sensory stimulation

Y Loewenstein, S Mahon, P Chadderton… - Nature …, 2005 - nature.com
A persistent change in neuronal activity after brief stimuli is a common feature of many
neuronal microcircuits. This persistent activity can be sustained by ongoing reverberant …