Accelerated cardiovascular disease is a frequent complication of renal disease. Chronic
kidney disease promotes hypertension and dyslipidemia, which in turn can contribute to the …

Cardiovascular disease (CVD) is prevalent worldwide and remains a leading cause of
death. Although substantial progress has been made in the diagnosis and treatment of CVD …

Introduction Exercise training is beneficial for reducing obesity. In particular, exercise
training can lower the catecholamine concentration in circulation. Renalase, whose …

Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …

The potential involvement of sympathetic overactivity has been neglected in this population
despite accumulating experimental and clinical evidence suggesting a crucial role of …

The kidney plays a fundamental role in maintaining body salt and fluid balance and blood
pressure homeostasis through the actions of its proximal and distal tubular segments of …

Aims Acute kidney injury (AKI) can limit the clinical use of cisplatin in cancer treatment. The
drivers of cisplatin-induced AKI include oxidative stress, mitochondrial dysfunction and …

The incidence of chronic kidney disease (CKD) is increasing worldwide, with more than 26
million people suffering from CKD in the United States alone. More patients with CKD die of …

Renalase is a novel flavoprotein, highly expressed in kidney and heart, which metabolizes
catecholamines and catecholamine-like substances via a superoxide (O2–)-dependent …

Annual cardiovascular mortality in patients with chronic kidney disease (CKD) is much
higher than in the general population. The rate of sudden cardiac death increases as the …