Despite the success of antiretroviral therapy (ART) for people living with HIV, lifelong
treatment is required and there is no cure. HIV can integrate in the host genome and persist …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that
has caused a worldwide pandemic of the human respiratory illness COVID-19, resulting in a …

The pandemic of coronavirus disease 2019 (COVID-19) is changing the world like never
before. This crisis is unlikely contained in the absence of effective therapeutics or vaccine …

The main barrier to HIV cure is a persistent reservoir of latently infected CD4+ T cells
harboring replication-competent provirus that fuels rebound viremia upon antiretroviral …

Despite the success of antiretroviral therapy (ART), there is currently no HIV cure and
treatment is life long. HIV persists during ART due to long-lived and proliferating latently …

Rare CD4 T cells that contain HIV under antiretroviral therapy represent an important barrier
to HIV cure,–, but the infeasibility of isolating and characterizing these cells in their natural …

Nonalcoholic steatohepatitis (NASH) has been linked with the gut-liver axis. Here, we
investigate the potential for repurposing disulfiram (DSF), a drug commonly used to treat …

Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a
global population of more than 35 million people living with HIV, there is intense interest in …

HIV persists in a small pool of latently infected cells despite antiretroviral therapy (ART).
Identifying cellular markers expressed at the surface of these cells may lead to novel …

In people living with HIV (PLWH) who are failing or unable to access combination
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …