Ferroptosis is an iron-dependent regulated cell death marked by excessive oxidative
phospholipids (PLs). The polyunsaturated fatty acids-containing phospholipids (PUFA-PLs) …

Background: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive
syndromes is a significant determinant of short-and long-term outcomes. Although …

Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean
pulmonary arterial pressure> 20 mm Hg. Rarely, PH presents as a primary disorder but is …

The European Respiratory Society (ERS) Research Seminar entitled “Pulmonary vascular
endothelium: orchestra conductor in respiratory diseases-highlights from basic research to …

Proponents for electronic cigarettes (E-cigs) claim that they are a safe alternative to tobacco-
based cigarettes; however, little is known about the long-term effects of exposure to E-cig …

Pulmonary hypertension (PH) because of chronic lung disease is categorized as Group 3
PH in the most recent classification system. Prevalence of these diseases is increasing over …

Rationale: Smoking-related microvascular loss causes end-organ damage in the kidneys,
heart, and brain. Basic research suggests a similar process in the lungs, but no large studies …

Despite recent therapeutic advances, pulmonary hypertension (PH) remains a fatal disease
due to the development of right ventricular (RV) failure. At present, no treatments targeted at …

Even mild pulmonary hypertension (PH) is associated with increased mortality and morbidity
in patients with chronic obstructive pulmonary disease (COPD). However, the underlying …

The burden of heart failure (HF) increases worldwide with an aging population, and there is
a high unmet medical need in both, heart failure with reduced ejection fraction (HFrEF) and …