Despite aggressive management consisting of surgery, radiation therapy (RT), and systemic
therapy given alone or in combination, a significant proportion of patients with brain tumors …

Simple Summary Patients with medulloblastoma receive treatment according to a risk
stratification, which is a combination of clinical and biological factors. To date there have …

Importance Medulloblastoma recurrence in patients who have previously received
irradiation has a dismal prognosis and lacks a standard salvage regimen. Objective To …

Simple Summary Medulloblastoma is the commonest malignant brain tumour of childhood.
Disease relapse following maximal multi-modal therapy including upfront craniospinal …

Background Many studies have demonstrated in the last years that once medulloblastoma
has recurred, the probability of regaining tumor control is poor despite salvage therapy …

Simple Summary A medulloblastoma recurrence is usually associated with an unfavorable
prognosis. The German P-HIT-REZ 2005 Study gathered data from patients with relapsed …

Simple Summary About 30% of patients with medulloblastoma experience recurrence,
which is usually incurable despite intensive chemotherapy. The aim of our retrospective …

Introduction: Medulloblastoma, an embryonal small round blue cell tumor primarily arising in
the posterior fossa, is the most common malignancy of the central nervous system in …

OBJECTIVE Recurrence of brain tumors in children after the initial course of treatment
remains a problem. This study evaluated the efficacy and safety of reirradiation using …

Simple Summary The treatment options for children with recurrent medulloblastoma are
often limited due to extensive previously received treatments after initial diagnosis …