Neuroinflammation is the coordinated response of the central nervous system (CNS) to
threats to its integrity posed by a variety of conditions, including autoimmunity, pathogens …

Investigation of cerebrospinal fluid (CSF) in the diagnostic work-up in suspected multiple
sclerosis (MS) patients has regained attention in the latest version of the diagnostic criteria …

Importance There is a lack of validated biomarkers for disability progression independent of
relapse activity (PIRA) in multiple sclerosis (MS). Objective To determine how serum glial …

While neurofilament light chain (NfL) measurement in serum is a well-established marker of
neuroaxonal damage in multiple sclerosis (MS), data on astroglial markers in serum are …

Objective To test the hypothesis that serum levels of glial fibrillary acidic protein (GFAP) and
neurofilament light chain (NfL), which are an intermediate astrocyte and neuron filaments …

Biomarkers can be thought of as multifaceted indicators of healthy status or of pathological
disorders. The study of multiple sclerosis can benefit from the use of biomarkers because of …

Progressive multiple sclerosis is characterised clinically by the gradual accrual of disability
independent of relapses and can occur with disease onset (primary progressive) or can be …

Neurological disorders (ND) are the central nervous system (CNS) related complications
originated by enhanced oxidative stress, mitochondrial failure and overexpression of …

Multiple sclerosis (MS) is a chronic autoimmune disease that impacts the central nervous
system and can result in disability. Although the prevalence of MS has increased in India …

Brain inflammation, characterized by increased microglia and astrocyte activation, increases
during aging and is a key feature of neurodegenerative diseases, such as Alzheimer's …