Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease
Recent advances in biomaterials, microfabrication, microfluidics, and cell biology have led to
the development of organ-on-a-chip devices that can reproduce key functions of various …
the development of organ-on-a-chip devices that can reproduce key functions of various …
Microfluidics for neuronal cell and circuit engineering
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …
communities has enabled addressing a broad range of questions at the molecular, cellular …
A review on microfluidics manipulation of the extracellular chemical microenvironment and its emerging application to cell analysis
Spatiotemporal manipulation of extracellular chemical environments with simultaneous
monitoring of cellular responses plays an essential role in exploring fundamental biological …
monitoring of cellular responses plays an essential role in exploring fundamental biological …
Microfluidics as an emerging precision tool in developmental biology
Microfluidics has become a precision tool in modern biology. It enables omics data to be
obtained from individual cells, as compared to averaged signals from cell populations, and it …
obtained from individual cells, as compared to averaged signals from cell populations, and it …
[HTML][HTML] Engineered neural circuits for modeling brain physiology and neuropathology
The neural circuits of the central nervous system are the regulatory pathways for feeling,
motion control, learning, and memory, and their dysfunction is closely related to various …
motion control, learning, and memory, and their dysfunction is closely related to various …
Functional bioengineered models of the central nervous system
The functional complexity of the central nervous system (CNS) is unparalleled in living
organisms. Its nested cells, circuits and networks encode memories, move bodies and …
organisms. Its nested cells, circuits and networks encode memories, move bodies and …
Gradient conducting polymer surfaces with netrin-1-conjugation promote axon guidance and neuron transmission of human iPSC-derived retinal ganglion cells
JW She, CM Young, SJ Chou, YR Wu, YT Lin… - Biomaterials, 2025 - Elsevier
Major advances have been made in utilizing human-induced pluripotent stem cells (hiPSCs)
for regenerative medicine. Nevertheless, the delivery and integration of hiPSCs into target …
for regenerative medicine. Nevertheless, the delivery and integration of hiPSCs into target …
Multiscale brain research on a microfluidic chip
One major challenge in current brain research is generating an integrative understanding of
the brain's functions and disorders from its multiscale neuronal architectures and …
the brain's functions and disorders from its multiscale neuronal architectures and …
A radial microfluidic platform for higher throughput chemotaxis studies with individual gradient control
J Wu, A Kumar-Kanojia, S Hombach-Klonisch… - Lab on a Chip, 2018 - pubs.rsc.org
Chemotaxis plays a fundamental role in immune defense and cancer metastasis.
Microfluidic devices are increasingly applied to studying chemotaxis, owing to their …
Microfluidic devices are increasingly applied to studying chemotaxis, owing to their …