Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

The Martini model, a coarse-grained force field for biomolecular simulations, has found a
broad range of applications since its release a decade ago. Based on a building block …

The Martini coarse-grained force field has been successfully used for simulating a wide
range of (bio) molecular systems. Recent progress in our ability to test the model against …

Molecular dynamics simulations reveal substructures within the liquid-ordered phase of lipid
bilayers. These substructures, identified in a 10 μs all-atom trajectory of liquid-ordered/liquid …

The main biological cause of oxysterols is the oxidation of cholesterol. They differ from
cholesterol by the presence of additional polar groups that are typically hydroxyl, keto …

Lipids rafts are considered to be functional nanoscale membrane domains enriched in
cholesterol and sphingolipids, characteristic in particular of the external leaflet of cell …

Qaiser Waheed, Olle Edholm. Molecular dynamics simulations of atomistic models show the
ordering and condensing effect of the cholesterol on phospholipid bilayers. Such …

As a result of their unique physical properties, biological membrane mimetics, such as
liposomes, are used in a broad range of scientific and technological applications …

Influenza virus infects cells by binding to sialylated glycans on the cell surface. While the
chemical structure of these glycans determines hemagglutinin–glycan binding affinity …

Non-enzymatic lipid peroxidation may change biomembrane structure and function. Here,
we employed molecular dynamics simulations to study the effects of either phospholipid or …