[HTML][HTML] Multiple myeloma current treatment algorithms

SV Rajkumar, S Kumar - Blood cancer journal, 2020 - nature.com
The treatment of multiple myeloma (MM) continues to evolve rapidly with arrival of multiple
new drugs, and emerging data from randomized trials to guide therapy. Along the disease …

Consensus guidelines and recommendations for infection prevention in multiple myeloma: a report from the International Myeloma Working Group

NS Raje, E Anaissie, SK Kumar, S Lonial… - The Lancet …, 2022 - thelancet.com
Infection remains the leading cause of morbidity and mortality in patients with multiple
myeloma because of the cumulative effect of disease, treatment, and host-related factors …

Multiple myeloma: 2022 update on diagnosis, risk stratification, and management

SV Rajkumar - American journal of hematology, 2022 - Wiley Online Library
Abstract Disease Overview Multiple myeloma accounts for approximately 10% of
hematologic malignancies. Diagnosis The diagnosis requires≥ 10% clonal bone marrow …

Second revision of the International Staging System (R2-ISS) for overall survival in multiple myeloma: a European Myeloma Network (EMN) report within the …

M D'agostino, DA Cairns, JJ Lahuerta… - Journal of clinical …, 2022 - ascopubs.org
PURPOSE Patients with newly diagnosed multiple myeloma (NDMM) show heterogeneous
outcomes, and approximately 60% of them are at intermediate-risk according to the Revised …

Daratumumab, carfilzomib, lenalidomide, and dexamethasone with minimal residual disease response-adapted therapy in newly diagnosed multiple myeloma

LJ Costa, S Chhabra, E Medvedova… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE The MASTER trial combined daratumumab, carfilzomib, lenalidomide, and
dexamethasone (Dara-KRd) in newly diagnosed multiple myeloma (NDMM), using minimal …

Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone …

M Cavo, F Gay, M Beksac, L Pantani… - The Lancet …, 2020 - thelancet.com
Background The emergence of highly active novel agents has led some to question the role
of autologous haematopoietic stem-cell transplantation (HSCT) and subsequent …

[HTML][HTML] Lenalidomide, bortezomib, and dexamethasone with transplantation for myeloma

M Attal, V Lauwers-Cances, C Hulin… - … England Journal of …, 2017 - Mass Medical Soc
Background High-dose chemotherapy plus autologous stem-cell transplantation has been
the standard treatment for newly diagnosed multiple myeloma in adults up to 65 years of …

Lenalidomide maintenance after autologous stem-cell transplantation in newly diagnosed multiple myeloma: a meta-analysis

PL McCarthy, SA Holstein, MT Petrucci… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Lenalidomide maintenance therapy after autologous stem-cell transplantation
(ASCT) demonstrated prolonged progression-free survival (PFS) versus placebo or …

Effect of tandem autologous stem cell transplant vs single transplant on event-free survival in patients with high-risk neuroblastoma: a randomized clinical trial

JR Park, SG Kreissman, WB London, A Naranjo… - Jama, 2019 - jamanetwork.com
Importance Induction chemotherapy followed by high-dose therapy with autologous stem
cell transplant and subsequent antidisialoganglioside antibody immunotherapy is standard …

Revised international staging system for multiple myeloma: a report from International Myeloma Working Group

A Palumbo, H Avet-Loiseau, S Oliva… - Journal of clinical …, 2015 - ascopubs.org
Purpose The clinical outcome of multiple myeloma (MM) is heterogeneous. A simple and
reliable tool is needed to stratify patients with MM. We combined the International Staging …