Early life exposure to per-and polyfluoroalkyl substances (PFAS) and latent health outcomes: A review including the placenta as a target tissue and possible driver of …

BE Blake, SE Fenton - Toxicology, 2020 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are ubiquitous drinking water contaminants of
concern due to mounting evidence implicating adverse health outcomes associated with …

[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

P Guerby, O Tasta, A Swiader, F Pont, E Bujold… - Redox biology, 2021 - Elsevier
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

Endovascular trophoblast and spiral artery remodeling

Y Sato - Molecular and cellular endocrinology, 2020 - Elsevier
Spiral artery remodeling, which is indispensable for successful pregnancy, is accomplished
by endovascular trophoblasts that move upstream along the arterial wall, replace the …

Maternal microbiome and infections in pregnancy

M Amir, JA Brown, SL Rager, KZ Sanidad… - Microorganisms, 2020 - mdpi.com
Pregnancy induces unique changes in maternal immune responses and metabolism.
Drastic physiologic adaptations, in an intricately coordinated fashion, allow the maternal …

Animal models of preeclampsia: causes, consequences, and interventions

KL Gatford, PH Andraweera, CT Roberts, AS Care - Hypertension, 2020 - Am Heart Assoc
Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …

Regulation of uterine spiral artery remodeling: a review

ED Albrecht, GJ Pepe - Reproductive Sciences, 2020 - Springer
Extravillous trophoblast remodeling of the uterine spiral arteries is essential for promoting
blood flow to the placenta and fetal development, but little is known about the regulation of …

The role of nutrients in human neurodevelopment and their potential to prevent neurodevelopmental adversity

S Heland, N Fields, SJ Ellery, M Fahey… - Frontiers in Nutrition, 2022 - frontiersin.org
Nutritional deficits or excesses affect a huge proportion of pregnant women worldwide.
Maternal nutrition has a significant influence on the fetal environment and can dramatically …

The role of nitric oxide, ADMA, and homocysteine in the etiopathogenesis of preeclampsia

W Dymara-Konopka, M Laskowska - International Journal of Molecular …, 2019 - mdpi.com
Preeclampsia is a serious, pregnancy-specific, multi-organ disease process of compound
aetiology. It affects 3–6% of expecting mothers worldwide and it persists as a leading cause …

The L-NAME mouse model of preeclampsia and impact to long-term maternal cardiovascular health

N de Alwis, NK Binder, S Beard… - Life science …, 2022 - life-science-alliance.org
Preeclampsia affects∼ 2–8% of pregnancies worldwide. It is associated with increased long-
term maternal cardiovascular disease risk. This study assesses the effect of the …

Placental extracellular vesicles and pre‐eclampsia

J Schuster, SB Cheng, J Padbury… - American journal of …, 2021 - Wiley Online Library
Pre‐eclampsia is a hypertensive disease of pregnancy characterized by new‐onset
hypertension, with either proteinuria and/or organ dysfunction. Pre‐eclampsia is a leading …