Two-dimensional (2D) optical spectroscopy utilizing multiple ultrafast coherent laser pulses
in the infrared or UV-vis frequency range has been used to study protein structure and …

We review two-dimensional infrared (2D IR) spectroscopy of the amide I protein backbone
vibration. Amide I modes are known for secondary structural sensitivity derived from their …

Quantum mechanics provides the most accurate microscopic description of the world around
us, yet the interface between quantum mechanics and biology is only now being explored …

Two-Dimensional Optical Spectroscopy discusses the principles and applications of newly
emerging two-dimensional vibrational and optical spectroscopy techniques. It provides a …

Abstract Chimeric Ag receptors (CARs) expressed in T cells permit the redirected lysis of
tumor cells in an MHC-unrestricted manner. In the Jurkat T cell model system, expression of …

The first step toward understanding most of the chemical and biological processes in
condensed phases is to accurately describe solute− solvent interaction energy and to …

The advent of laser-based sources of ultrafast infrared pulses has extended the study of very
fast molecular dynamics to the observation of processes manifested through their effects on …

Infrared (IR) spectroscopy of the amide I band has been widely utilized for the analysis of
peptides and proteins. Theoretical modeling of IR spectra of proteins requires an accurate …

Two-dimensional infrared spectroscopy of amide I vibrations is increasingly being used to
study the structure and dynamics of proteins and peptides. Amide I, a primarily carbonyl …

We describe a methodology for studying protein kinetics using a rapid-scan technology for
collecting 2D IR spectra. In conjunction with isotope labeling, 2D IR spectroscopy is able to …