Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

Z Chen, R Tian, Z She, J Cai, H Li - Free Radical Biology and Medicine, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Metabolic effects of intermittent fasting

RE Patterson, DD Sears - Annual review of nutrition, 2017 - annualreviews.org
The objective of this review is to provide an overview of intermittent fasting regimens,
summarize the evidence on the health benefits of intermittent fasting, and discuss …

[HTML][HTML] Mitochondrial (dys) function and insulin resistance: from pathophysiological molecular mechanisms to the impact of diet

D Sergi, N Naumovski, LK Heilbronn… - Frontiers in …, 2019 - frontiersin.org
Mitochondrial dysfunction has been implicated in the pathogenesis of insulin resistance, the
hallmark of type 2 diabetes mellitus (T2DM). However, the cause-effect relationship remains …

Intermittent fasting: is the wait worth the weight?

MC Stockman, D Thomas, J Burke, CM Apovian - Current obesity reports, 2018 - Springer
Abstract Purpose of Review We review the underlying mechanisms and potential benefits of
intermittent fasting (IF) from animal models and recent clinical trials. Recent Findings …

The neuroprotective effects of intermittent fasting on brain aging and neurodegenerative diseases via regulating mitochondrial function

Y Zhao, M Jia, W Chen, Z Liu - Free Radical Biology and Medicine, 2022 - Elsevier
Intermittent fasting (IF) has been studied for its effects on lifespan and the prevention or
delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria …

Cardiac ageing: extrinsic and intrinsic factors in cellular renewal and senescence

NA Gude, KM Broughton, F Firouzi… - Nature Reviews …, 2018 - nature.com
Cardiac ageing manifests as a decline in function leading to heart failure. At the cellular
level, ageing entails decreased replicative capacity and dysregulation of cellular processes …

Circadian rhythms in diet-induced obesity

A Engin - Obesity and lipotoxicity, 2017 - Springer
The biological clocks of the circadian timing system coordinate cellular and physiological
processes and synchronizes these with daily cycles, feeding patterns also regulates …

Intermittent fasting and 'metabolic switch': Effects on metabolic syndrome, prediabetes and type 2 diabetes

A Rajpal, F Ismail‐Beigi - Diabetes, Obesity and Metabolism, 2020 - Wiley Online Library
Various intermittent fasting (IF) dietary plans have gained popularity among obese
individuals in recent years as a means of achieving weight loss. However, studies …

Altered mitochondrial metabolism in the insulin‐resistant heart

M Makrecka‐Kuka, E Liepinsh, AJ Murray… - Acta …, 2020 - Wiley Online Library
Obesity‐induced insulin resistance and type 2 diabetes mellitus can ultimately result in
various complications, including diabetic cardiomyopathy. In this case, cardiac dysfunction is …

Solving the conundrum of intra‐specific variation in metabolic rate: A multidisciplinary conceptual and methodological toolkit: New technical developments are …

NB Metcalfe, J Bellman, P Bize, PU Blier, A Crespel… - …, 2023 - Wiley Online Library
Researchers from diverse disciplines, including organismal and cellular physiology, sports
science, human nutrition, evolution and ecology, have sought to understand the causes and …