Tropical, vector-borne, and neglected diseases with a limited number of medication
therapies include Leishmaniasis, Malaria, Chagas and Human African Trypanosomiasis …

Current therapies of leishmaniasis and Chagas disease, two of the most widespread
neglected tropical diseases, have limited efficacy and toxic side effects. In this regard …

Aim: Our objective was to investigate the trypanocidal effect of the chalcone (2 E, 4 E)-1-(2-
hydroxy-3, 4, 6-trimethoxyphenyl)-5-phenylpenta-2, 4-dien-1-one (CPNC). Material & …

Objective: In this study, a series of synthetic hydroxylated (5-10) and prenylated (10-17)
acetophenones, chalcones (18-20) and a flavone (21) have been synthesized and …

Abstract Lysiphyllum binatum (Blanco) de Wit in the Fabaceae family, despite its traditional
medicinal uses, has not been the subject of prior scientific inquiry into its chemical and …

The most important achievements on the synthesis of O-and S-6-membered heterocycles
published in 2021 are reviewed. This personal overview is focused on the developments …

Current therapies of leishmaniasis and Chagas disease, two of the most widespread
neglected tropical diseases, have limited efficacy and toxic side effects. In this regard …