Living cells are constantly exposed to mechanical stimuli arising from the surrounding
extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes …

The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

We have developed two-step process that uses sequential vitamin B2-induced UVA
crosslinking and thermal gelation to solidify decellularized extracellular matrix (dECM) …

The term 'mechanosensation'describes the capacity of cells to translate mechanical stimuli
into the coordinated regulation of intracellular signals, cellular function, gene expression …

The field of cardiac tissue engineering has made significant strides over the last few
decades, highlighted by the development of human cell derived constructs that have shown …

Background—Human pluripotent stem cell–derived cardiomyocytes (hPSC-CMs)
monolayers generated to date display an immature embryonic-like functional and structural …

In the past few years, a considerable amount of effort has been devoted toward the
development of biomimetic scaffolds for cardiac tissue engineering. However, most of the …

Rationale: Cardiac ECM (extracellular matrix) comprises a dynamic molecular network
providing structural support to heart tissue function. Understanding the impact of ECM …

Dystrophin is the central protein of the dystrophin-glycoprotein complex (DGC) in skeletal
and heart muscle cells. Dystrophin connects the actin cytoskeleton to the extracellular matrix …

The development of hydrogel-based biomaterials represents a promising approach to
generating new strategies for tissue engineering and regenerative medicine. In order to …