In the high-stakes arena of drug discovery, the journey from bench to bedside is hindered by
a daunting 92% failure rate, primarily due to unpredicted toxicities and inadequate …

Synthetic extracellular matrix (ECM) mimics that can recapitulate the complex biochemical
and mechanical nature of native tissues are needed for advanced models of development …

Biotechnological processes are essential for developing economies that aim to stand out in
future markets. The use of bioreactors is one of the most important unit operations of …

Biomimetic cell culture, which involves creating a biomimetic microenvironment for cells in
vitro by engineering approaches, has aroused increasing interest given that it maintains the …

Stem cells (SCs) have been used therapeutically for decades, yet their applications are
limited by factors such as the risk of immune rejection and potential tumorigenicity …

Three-dimensional bioprinting has emerged as an appealing approach for creating
functional tissues; however, a lack of suitable bioinks with high cell density and printability …

Advancing biofabrication toward manufacturing living constructs with well‐defined
architectures and increasingly biologically relevant cell densities is highly desired to mimic …

Our ability to produce human-scale bio-manufactured organs is critically limited by the need
for vascularization and perfusion. For tissues of variable size and shape, including arbitrarily …

Induced pluripotent stem cell (iPSC) technology has revolutionized various fields, including
stem cell research, disease modeling, and regenerative medicine. The evolution of iPSC …

The biofabrication of complex human tissues to recapitulate organ-specific architecture and
function requires a combination of engineering control and intrinsic self-assembly. Organoid …