The development of a patient-centered approach to medicine is gradually allowing more
patients to be involved in their own medical decisions. However, this change is not …

ABSTRACT OBJECTIVES We conducted a review of the peer-reviewed literature since 2003
to catalogue reported methods of stakeholder engagement in comparative effectiveness …

Although efficacy and effectiveness studies are both important when evaluating
interventions, they serve distinct purposes and have different study designs. Unfortunately …

Understanding and improving the prognosis of a disease or health condition is a priority in
clinical research and practice. In this article, the authors introduce a framework of four …

Non-randomised studies of the effects of interventions are critical to many areas of
healthcare evaluation, but their results may be biased. It is therefore important to understand …

The objective was to update previous evidence‐based medicine reviews of treatments for
motor symptoms of Parkinson's disease published between 2002 and 2005. Level I …

In patients with cystic fibrosis (CF) lung damage secondary to chronic infection is the main
cause of death. Treatment of lung disease to reduce the impact of infection, inflammation …

Employment is the highest priority for many people with severe mental illness and it is a
central aspect of recovery. Over the past two decades, the Individual Placement and Support …

Background Evidence-based medicine (EBM) has always required integration of patient
values with 'best'clinical evidence. It is widely recognized that scientific practices and …

Aims: Stakeholder engagement is fundamental to comparative effectiveness research
(CER), but lacks consistent terminology. This paper aims to define stakeholder engagement …