Zebrafish models for human skeletal disorders

M Marí-Beffa, AB Mesa-Román, I Duran - Frontiers in Genetics, 2021 - frontiersin.org
In 2019, the Nosology Committee of the International Skeletal Dysplasia Society provided an
updated version of the Nosology and Classification of Genetic Skeletal Disorders. This is a …

[HTML][HTML] MicroRNAs: pleiotropic players in congenital heart disease and regeneration

SC Hoelscher, SA Doppler, M Dreßen… - Journal of thoracic …, 2017 - ncbi.nlm.nih.gov
Congenital heart disease (CHD) is the leading cause of infant death, affecting approximately
4–14 live births per 1,000. Although surgical techniques and interventions have improved …

Combining results from distinct microRNA target prediction tools enhances the performance of analyses

AC Oliveira, LA Bovolenta, PG Nachtigall… - Frontiers in …, 2017 - frontiersin.org
Target prediction is generally the first step toward recognition of bona fide microRNA
(miRNA)-target interactions in living cells. Several target prediction tools are now available …

Post-transcriptional regulation of molecular determinants during cardiogenesis

E Lozano-Velasco, C Garcia-Padilla… - International Journal of …, 2022 - mdpi.com
Cardiovascular development is initiated soon after gastrulation as bilateral precardiac
mesoderm is progressively symmetrically determined at both sides of the developing …

Characterisation of miRNA expression in dental pulp cells during epigenetically-driven reparative processes

M Kearney, PR Cooper, AJ Smith… - International journal of …, 2023 - mdpi.com
Within regenerative endodontics, exciting opportunities exist for the development of next-
generation targeted biomaterials that harness epigenetic machinery, including microRNAs …

MicroRNA-206 promotes lipopolysaccharide-induced inflammation injury via regulation of IRAK1 in MRC-5 cells

H Chu, X Qu, F Wang, J Chang, R Cheng… - International …, 2019 - Elsevier
Background MicroRNAs (miRNAs) have been reported to play crucial role in the airway
inflammatory diseases. However, the involvement of miR-206 in airway inflammatory …

miR-182-5p is an evolutionarily conserved Tbx5 effector that impacts cardiac development and electrical activity in zebrafish

E Guzzolino, M Pellegrino, N Ahuja, D Garrity… - Cellular and Molecular …, 2020 - Springer
To dissect the TBX5 regulatory circuit, we focused on microRNAs (miRNAs) that collectively
contribute to make TBX5 a pivotal cardiac regulator. We profiled miRNAs in hearts isolated …

Potential biomarkers of abnormal osseointegration of implants in type II diabetes mellitus

L Wang, Z Gao, C Liu, J Li - BMC Oral Health, 2021 - Springer
Background Type II diabetes mellitus (T2DM) is an important risk factor for osseointegration
of implants. The aim of this study was to explore key genes of T2DM affecting bone …

Screening and identification of miRNAs regulating Tbx4/5 genes of Pampus argenteus

C Zhang, S Zhang, M Liu, Y Wang, D Wang, S Xu - PeerJ, 2022 - peerj.com
Background Silver pomfret (Pampus argenteus) is one of the most widely distributed and
economically important pelagic fish species. However, an unique morphological feature of …

Interplay between cardiac transcription factors and non-coding RNAs in predisposing to atrial fibrillation

AT Mikhailov, M Torrado - Journal of Molecular Medicine, 2018 - Springer
There is growing evidence that putative gene regulatory networks including cardio-enriched
transcription factors, such as PITX2, TBX5, ZFHX3, and SHOX2, and their effector/target …